Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 4/20 | 0.47 |
| ▸ | BRD4 | O60885 | 3/20 | 0.43 |
| ▸ | SGMS2 | Q8NHU3 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6858810 | 0.87 | LIPG (0.47) | LIPGBRD4SGMS2HPGDMAPT | |
| SCHEMBL13339884 | 0.86 | SPHK2 (0.48) | LIPGBRD4SGMS2HPGDLMNA | |
| SCHEMBL6864646 | 0.85 | LIPG (0.45) | LIPGBRD4SGMS2HPGDMAPT | |
| SCHEMBL8335413 | 0.84 | BRD4 (0.48) | LIPGBRD4SGMS2HPGDMAPT | |
| SCHEMBL16789591 | 0.84 | GLRA1 (0.47) | LIPGHPGDLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL2240565 | 0.83 | HPGD (0.44) | LIPGHPGDLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL8892680 | 0.83 | APP (0.45) | LIPGHPGDMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL8333545 | 0.82 | LIPG (0.43) | LIPGBRD4SGMS2HPGDLMNA | |
| SCHEMBL19709882 | 0.82 | MAOB (0.48) | LIPGBRD4HPGDLMNAMAPT | |
| SCHEMBL13339929 | 0.81 | LIPG (0.41) | LIPGBRD4SGMS2HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5892029-A | HIGHLY EFFECTIVE UPON BOTH INJECTION AND ORAL ADMINISTRATION. | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1999-04-06 | — | — | US | disclosed |