Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.43 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 4/20 | 0.41 |
| ▸ | LIPC | P11150 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 5/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13339884 | 0.94 | SPHK2 (0.48) | LIPGSPHK2BRD4LIPCNPC1 | |
| SCHEMBL8335413 | 0.92 | BRD4 (0.48) | LIPGSPHK2BRD4LIPCNPC1 | |
| SCHEMBL6858810 | 0.86 | LIPG (0.47) | LIPGBRD4LIPCNPC1RAB9A | |
| SCHEMBL13339929 | 0.86 | LIPG (0.41) | LIPGSPHK2BRD4LIPCNPC1 | |
| SCHEMBL8892680 | 0.84 | APP (0.45) | LIPGLIPCNPC1RAB9AKDM4E | |
| SCHEMBL13367279 | 0.84 | CNR2 (0.39) | LIPGLIPCSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL6864646 | 0.84 | LIPG (0.45) | LIPGBRD4LIPCNPC1RAB9A | |
| SCHEMBL8333370 | 0.82 | LIPG (0.47) | LIPGBRD4NPC1RAB9AKDM4E | |
| SCHEMBL5557571 | 0.81 | KDM4E (0.43) | BRD4NPC1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL13340013 | 0.80 | KLKB1 (0.52) | SPHK2BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7718781-B2 | Hydroxypyridonate and hydroxypyrimidinone chelating agents | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-05-18 | — | — | US | disclosed |
| US-5892029-A | HIGHLY EFFECTIVE UPON BOTH INJECTION AND ORAL ADMINISTRATION. | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1999-04-06 | — | — | US | disclosed |