Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 4/20 | 0.45 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | LIPC | P11150 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6864646 | 0.94 | LIPG (0.45) | LIPGALDH1A1MEN1KMT2ALIPC | |
| SCHEMBL13339929 | 0.89 | LIPG (0.41) | LIPGALDH1A1MEN1KMT2ALIPC | |
| SCHEMBL8335413 | 0.88 | BRD4 (0.48) | LIPGALDH1A1MEN1KMT2ALIPC | |
| SCHEMBL6858810 | 0.87 | LIPG (0.47) | LIPGALDH1A1MEN1KMT2ALIPC | |
| SCHEMBL13339884 | 0.86 | SPHK2 (0.48) | LIPGALDH1A1MEN1KMT2ALIPC | |
| SCHEMBL15104859 | 0.85 | LIPG (0.39) | LIPGALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL8333545 | 0.84 | LIPG (0.43) | LIPGALDH1A1MEN1KMT2ALIPC | |
| SCHEMBL8333370 | 0.83 | LIPG (0.47) | LIPGALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL21802399 | 0.82 | HDAC1 (0.37) | APPLIPGALDH1A1MEN1KMT2A | |
| SCHEMBL12356363 | 0.82 | KMT2A (0.40) | LIPGMEN1KMT2AGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5624901-A | CARBAMOYL SUBSTITUTED COMPOUNDS FOR CHELATE COMPOUNDS FOR MAGNETIC RESONANCE IMAGING | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1997-04-29 | — | — | US | disclosed |