Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 2/20 | 0.52 |
| ▸ | HTR2A | P28223 | 2/20 | 0.47 |
| ▸ | HTR2C | P28335 | 2/20 | 0.47 |
| ▸ | HTR2B | P41595 | 2/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | MDM2 | Q00987 | 6/20 | 0.42 |
| ▸ | TP53 | P04637 | 5/20 | 0.42 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8331072 | 0.84 | HTR2C (0.47) | SLC9A1HTR2AHTR2CHTR2BALOX5 | |
| SCHEMBL8333640 | 0.83 | SLC9A1 (0.50) | SLC9A1HTR2AHTR2CHTR2BALOX5 | |
| SCHEMBL8330436 | 0.83 | KDM1A (0.51) | SLC9A1HTR2AHTR2CHTR2BALOX5 | |
| SCHEMBL8332790 | 0.81 | SLC9A1 (0.56) | SLC9A1HTR2AHTR2CHTR2BALOX5 | |
| SCHEMBL8332794 | 0.80 | SLC9A1 (0.47) | SLC9A1HTR2AHTR2CHTR2BALOX5 | |
| SCHEMBL23993596 | 0.80 | HTR2A (0.51) | SLC9A1HTR2AHTR2CHTR2BMDM2 | |
| SCHEMBL27430078 | 0.79 | SLC9A1 (0.56) | SLC9A1ALOX5TP53 | |
| SCHEMBL24737578 | 0.74 | SLC9A1 (0.71) | SLC9A1HTR2AHTR2CHTR2BMDM2 | |
| SCHEMBL24737867 | 0.74 | SLC9A1 (0.71) | SLC9A1HTR2AHTR2CHTR2BMDM2 | |
| SCHEMBL24737580 | 0.74 | SLC9A1 (0.71) | SLC9A1HTR2AHTR2CHTR2BMDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5889031-A | CONTROLLING CIRCADIAN RHYTHMS | BRISTOL-MYERS SQUIBB COMPNAY (US) | 1999-03-30 | — | — | US | disclosed |
| US-5753709-A | N-acyl-2 aryl cyclopropylmethylamine derivatives as melatonergics | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-05-19 | — | — | US | disclosed |