Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 17/20 | 0.61 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | MTOR | P42345 | 1/20 | 0.45 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1383122 | 0.79 | F10 (0.60) | F10MTOR | |
| SCHEMBL14838714 | 0.79 | F10 (0.45) | F10 | |
| SCHEMBL8692897 | 0.79 | CA1 (0.66) | CA1CA2 | |
| SCHEMBL6181035 | 0.79 | F10 (0.60) | F10 | |
| SCHEMBL1380646 | 0.78 | F10 (0.62) | F10 | |
| SCHEMBL1679321 | 0.78 | F10 (0.65) | F10 | |
| SCHEMBL5629380 | 0.78 | F10 (0.72) | F10 | |
| SCHEMBL1380603 | 0.78 | F10 (0.59) | F10 | |
| SCHEMBL6182831 | 0.78 | F10 (0.59) | F10MTOR | |
| SCHEMBL1381539 | 0.78 | F10 (0.59) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004065369-A1 | CARBOXAMIDE DERIVATIVES AND THEIR USE AS FACTOR XA INHIBITORS | MERCK PATENT GMBH (DE) | 2004-08-05 | — | — | WO | disclosed |