Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | METAP1 | P53582 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | FYN | P06241 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | GRB2 | P62993 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CBFB | Q13951 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7952415 | 0.88 | CYP2C9 (0.56) | ADORA3CYP2C9CYP3A4METAP1MAPK1 | |
| SCHEMBL8335283 | 0.86 | NPSR1 (0.51) | ADORA3CYP2C9CYP3A4METAP1MAPK1 | |
| SCHEMBL8335971 | 0.86 | ADORA3 (0.45) | ADORA3CYP2C9CYP3A4METAP1MAPK1 | |
| SCHEMBL8334494 | 0.86 | KMT2A (0.48) | ADORA3CYP2C9CYP3A4NPSR1TDP1 | |
| SCHEMBL8335356 | 0.86 | KDM4E (0.52) | ADORA3CYP2C9CYP3A4METAP1NPSR1 | |
| SCHEMBL8335315 | 0.86 | ADORA3 (0.45) | ADORA3CYP2C9CYP3A4METAP1MAPK1 | |
| SCHEMBL8334301 | 0.84 | METAP1 (0.49) | ADORA3METAP1NPSR1LMNA | |
| SCHEMBL8338056 | 0.84 | METAP1 (0.48) | ADORA3CYP2C9CYP3A4METAP1MAPK1 | |
| SCHEMBL8336614 | 0.74 | KDM4E (0.54) | ADORA3CYP2C9CYP3A4METAP1MAPK1 | |
| SCHEMBL18473272 | 0.73 | ADORA3 (0.52) | ADORA3CYP2C9CYP3A4METAP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5969150-A | FLUORESCENT COMPOUNDS FOR MEDICAL DIAGNOSIS, DRUGS AND LABELS OR FUNGICIDES AND VIRICIDES | THE ROCKEFELLER UNIVERSITY (US) | 1999-10-19 | — | — | US | disclosed |