Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | KDM6B | O15054 | 1/20 | 0.52 |
| ▸ | KDM4A | O75164 | 1/20 | 0.52 |
| ▸ | KDM5C | P41229 | 1/20 | 0.52 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.52 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.52 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.52 |
| ▸ | METAP1 | P53582 | 2/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.43 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.42 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8336614 | 0.89 | KDM4E (0.54) | KDM4EKDM6BKDM4AKDM5CKDM4C | |
| SCHEMBL7952415 | 0.87 | CYP2C9 (0.56) | KDM4EMETAP1ADORA3CYP2C9CYP3A4 | |
| SCHEMBL8334151 | 0.86 | ADORA3 (0.46) | METAP1ADORA3CYP2C9CYP3A4DHODH | |
| SCHEMBL8335315 | 0.85 | ADORA3 (0.45) | KDM4EMETAP1ADORA3CYP2C9CYP3A4 | |
| SCHEMBL8334494 | 0.85 | KMT2A (0.48) | KDM4EADORA3CYP2C9CYP3A4NPSR1 | |
| SCHEMBL8335283 | 0.85 | NPSR1 (0.51) | KDM4EMETAP1ADORA3CYP2C9CYP3A4 | |
| SCHEMBL8335971 | 0.85 | ADORA3 (0.45) | KDM4EMETAP1ADORA3CYP2C9CYP3A4 | |
| SCHEMBL8334301 | 0.81 | METAP1 (0.49) | KDM4EMETAP1ADORA3NPSR1MAPT | |
| SCHEMBL31025274 | 0.77 | KDM4E (0.62) | KDM4EKDM6BKDM4AKDM5CKDM4C | |
| SCHEMBL863317 | 0.73 | KDM4E (0.74) | KDM4EKDM6BKDM4AKDM5CKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5969150-A | FLUORESCENT COMPOUNDS FOR MEDICAL DIAGNOSIS, DRUGS AND LABELS OR FUNGICIDES AND VIRICIDES | THE ROCKEFELLER UNIVERSITY (US) | 1999-10-19 | — | — | US | disclosed |