Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6721287 | 0.85 | SIGMAR1 (0.33) | SIGMAR1 | |
| SCHEMBL9438424 | 0.81 | SIGMAR1 (0.46) | SIGMAR1 | |
| SCHEMBL8329446 | 0.81 | LMNA (0.41) | SIGMAR1 | |
| SCHEMBL9438469 | 0.79 | SIGMAR1 (0.42) | SIGMAR1 | |
| SCHEMBL8334405 | 0.78 | SIGMAR1 (0.39) | SIGMAR1 | |
| SCHEMBL7619847 | 0.78 | SIGMAR1 (0.43) | SIGMAR1 | |
| SCHEMBL6720811 | 0.75 | SIGMAR1 (0.41) | SIGMAR1 | |
| SCHEMBL6721289 | 0.75 | SIGMAR1 (0.51) | SIGMAR1 | |
| SCHEMBL6717067 | 0.74 | SIGMAR1 (0.41) | SIGMAR1 | |
| SCHEMBL6717010 | 0.74 | SIGMAR1 (0.39) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999002145-A1 | COMBINATION DRUG THERAPIES COMPRISING AMINOGLYCOSIDE ANTIBIOTICS AND N,N'-DISUBSTITUTED GUANIDINES | CAMBRIDGE NEUROSCIENCE, INC. (US) | 1999-01-21 | — | — | WO | claimed |
| WO-1999002145-A1 | COMBINATION DRUG THERAPIES COMPRISING AMINOGLYCOSIDE ANTIBIOTICS AND N,N'-DISUBSTITUTED GUANIDINES | CAMBRIDGE NEUROSCIENCE, INC. (US) | 1999-01-21 | — | — | WO | disclosed |
| EP-0517852-A4 | — | — | 1994-03-02 | — | — | EP | disclosed |
| EP-0517852-A1 | TRI- AND TETRA-SUBSTITUTED GUANIDINES AND THEIR USE AS EXCITATORY AMINO ACID ANTAGONISTS | STATE OF OREGON, acting through OREGON STATE BOARD OF HIGHER EDUCATION, acting for OREGON HEALTH SC. UNIV. AND UNIV. OF OREGON (US) | 1992-12-16 | — | — | EP | disclosed |
| WO-1991012797-A1 | TRI- AND TETRA-SUBSTITUTED GUANIDINES AND THEIR USE AS EXCITATORY AMINO ACID ANTAGONISTS | STATE OF OREGON, acting by and through THE OREGON STATE BOARD OF HIGHER EDUCATION, acting for and on behalf of THE OREGON HEALF SCIENCES UNIVERSITY (US) | 1991-09-05 | — | — | WO | disclosed |