Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 19/20 | 0.71 |
| ▸ | DPP8 | Q6V1X1 | 8/20 | 0.71 |
| ▸ | DPP7 | Q9UHL4 | 7/20 | 0.71 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5037120 | 0.88 | DPP4 (0.75) | DPP4DPP8DPP7KCNH2 | |
| SCHEMBL14278758 | 0.84 | DPP4 (0.75) | DPP4DPP8DPP7KCNH2 | |
| SCHEMBL5036584 | 0.80 | DPP4 (0.80) | DPP4DPP8DPP7KCNH2 | |
| SCHEMBL5036582 | 0.80 | DPP4 (0.80) | DPP4DPP8DPP7KCNH2 | |
| SCHEMBL5132150 | 0.79 | DPP4 (0.77) | DPP4DPP8DPP7KCNH2 | |
| SCHEMBL14278852 | 0.79 | DPP4 (0.77) | DPP4DPP8DPP7KCNH2 | |
| Hydrochloric Acid SCHEMBL5037269 | 0.78 | DPP4 (0.76) | DPP4DPP8DPP7KCNH2 | |
| SCHEMBL21067975 | 0.77 | DPP4 (1.00) | DPP4DPP8DPP7KCNH2 | |
| SCHEMBL388929 | 0.77 | DPP4 (1.00) | DPP4DPP8DPP7KCNH2 | |
| SCHEMBL21067640 | 0.77 | DPP4 (1.00) | DPP4DPP8DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1556362-B1 | BETA-AMINO HETEROCYCLIC DIPEPTIDYL PEPTIDASE INHIBITORS FOR THE TREATMENT OR PREVENTION OF DIABETES | MERCK & CO INC (US) | 2008-03-26 | — | — | EP | disclosed |
| WO-2004037169-A2 | BETA-AMINO HETEROCYCLIC DIPEPTIDYL PEPTIDASE INHIBITORS FOR THE TREATMENT OR PREVENTION OF DIABETES | MERCK & CO., INC. (US) | 2004-05-06 | — | — | WO | disclosed |