SCHEMBL8334665

SCHEMBL8334665

O=P(O)(O)C(O)(O)P(=O)(O)O

nearest known ligand 0.50

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.50
PGK1 P00558 1/20 0.44
PGK2 P07205 1/20 0.44
FDPS P14324 13/20 0.39
PDE3A Q14432 2/20 0.38
ADRB3 P13945 1/20 0.38
PDE4D Q08499 1/20 0.38
CA2 P00918 1/20 0.36
GGPS1 O95749 5/20 0.33
SLC34A1 Q06495 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11489313 0.73 LMNA (0.50) LMNAPGK1PGK2FDPSPDE3A
SCHEMBL11881792 0.73 LMNA (0.50) LMNAPGK1PGK2FDPSPDE3A
SCHEMBL4649888 0.70
SCHEMBL27585056 0.70
SCHEMBL134918 0.70
SCHEMBL2490730 0.67 LMNA (0.44) LMNAPGK1PGK2FDPSPDE3A
Phosphoric Acid SCHEMBL9131678 0.64
Phosphoric Acid SCHEMBL29136242 0.64
Phosphoric Acid SCHEMBL3639714 0.64
Phosphoric Acid SCHEMBL2861492 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0802919-A4 RAPIDLY CLEARING TECHNETIUM-99m PHOSPHONATE SKELETAL IMAGING AGENTS MALLINCKRODT MEDICAL INC (US) 1999-08-18 EP disclosed
EP-0802919-A1 RAPIDLY CLEARING TECHNETIUM-99m PHOSPHONATE SKELETAL IMAGING AGENTS MALLINCKRODT MEDICAL, INC. (US) 1997-10-29 EP disclosed
WO-1995033757-A1 RAPIDLY CLEARING TECHNETIUM-99m PHOSPHONATE SKELETAL IMAGING AGENTS MALLINCKRODT MEDICAL, INC. (US) 1995-12-14 WO disclosed
US-4497744-A Gentisic acid salts as radiographic scanning agent stabilizers MALLINCKRODT, INC. (US) 1985-02-05 US disclosed
EP-0006658-B1 RADIOACTIVE SCANNING AGENTS WITH HYDROQUINONE AS STABILIZER AND METHOD FOR PREPARING THEM THE PROCTER & GAMBLE COMPANY (US) 1982-08-11 EP disclosed
US-4330537-A PHOSPHONATE COMPOUNDS AND VITAMIN D DERIVATIVES USEFUL AGAINST OSTEOPORSIS THE PROCTER & GAMBLE COMPANY (US) 1982-05-18 US disclosed
EP-0006659-B1 COMPOSITIONS USEFUL IN THE PREPARATION OF STABILIZED RADIOGRAPHIC SCANNING AGENTS, A METHOD OF PREPARING THEM AND THE USE OF STANNOUS GENTISILATE AS STABILIZER IN THESE COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1982-04-21 EP disclosed
EP-0004684-B1 STABILIZED RADIOGRAPHIC SCANNING AGENTS AND METHOD FOR PREPARING THEM THE PROCTER & GAMBLE COMPANY (US) 1981-09-16 EP disclosed
US-4234562-A WITH TECHNETIUM-99, A STANNOUS, FERROUS OR CHROMOUS CHLORIDE OR SULFATE, AN ORGANIC PHOSPHONIC ACID THE PROCTER & GAMBLE COMPANY (US) 1980-11-18 US disclosed
US-4233284-A GENESTIC ACID, SALT OR ESTER THEREOF IN COMBINATION WITH A PERTECHNETATE REDUCING AGENT BECOMES LOCALIZED IN SPECIFIC BODY ORGANS OR BONES THE PROCTER & GAMBLE COMPANY (US) 1980-11-11 US disclosed
US-4232000-A GENTISYL ALCOHOL, REDUCING AGENT THE PROCTER & GAMBLE COMPANY (US) 1980-11-04 US disclosed
US-4230700-A ADMINISTERING AN ORGANIC MONO- OR DIPHOSPHONATE AND A VITAMIN-D-LIKE ANTIRACHITIC COMPOUND THE PROCTER & GAMBLE COMPANY (US) 1980-10-28 US disclosed
US-4229427-A REDUCING AGENTS FOR PERTECHNETATE; MEDICAL DIAGNOSIS THE PROCTER & GAMBLE COMPANY (US) 1980-10-21 US disclosed
EP-0006659-A1 Compositions useful in the preparation of stabilized radiographic scanning agents, a method of preparing them and the use of stannous gentisilate as stabilizer in these compositions THE PROCTER & GAMBLE COMPANY (US) 1980-01-09 EP disclosed
EP-0006658-A1 Radioactive scanning agents with hydroquinone as stabilizer and method for preparing them THE PROCTER & GAMBLE COMPANY (US) 1980-01-09 EP disclosed
EP-0004684-A2 Stabilized radiographic scanning agents and method for preparing them THE PROCTER & GAMBLE COMPANY (US) 1979-10-17 EP disclosed
US-3983227-A TECHNETIUM THE PROCTER & GAMBLE COMPANY (US) 1976-09-28 US disclosed
US-3965254-A Compositions for the treatment of calcific tumors THE PROCTER & GAMBLE COMPANY (US) 1976-06-22 US disclosed