SCHEMBL2490730

SCHEMBL2490730

O=P(O)(O)C(P(=O)(O)O)(P(=O)(O)O)P(=O)(O)O

nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.44
FDPS P14324 6/20 0.41
PGK1 P00558 2/20 0.39
PGK2 P07205 2/20 0.39
CA2 P00918 1/20 0.39
SLC34A1 Q06495 1/20 0.36
KDM4E B2RXH2 2/20 0.33
PDE3A Q14432 2/20 0.33
MMP2 P08253 1/20 0.33
THRB P10828 1/20 0.33
MAPK1 P28482 1/20 0.33
HSD17B10 Q99714 1/20 0.33
ADRB3 P13945 1/20 0.33
PDE4D Q08499 1/20 0.33
BLM P54132 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
CYP2C19 P33261 1/20 0.32
KMT2A Q03164 1/20 0.32
PTPN1 P18031 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylenediamine SCHEMBL3636616 0.82 FDPS (0.50) LMNAFDPSPDE3AADRB3PDE4D
SCHEMBL2803768 0.67
Phosphoric Acid SCHEMBL5907 0.65 CA2 (0.56) LMNAFDPSPGK1PGK2CA2
Phosphoric Acid SCHEMBL8851940 0.65 CA2 (0.56) LMNAFDPSPGK1PGK2CA2
Phosphoric Acid SCHEMBL8844890 0.65 CA2 (0.56) LMNAFDPSPGK1PGK2CA2
Phosphoric Acid SCHEMBL1332284 0.65
Phosphoric Acid SCHEMBL3788505 0.65 CA2 (0.56) LMNAFDPSPGK1PGK2CA2
Phosphoric Acid SCHEMBL36090 0.65 CA2 (0.56) LMNAFDPSPGK1PGK2CA2
Phosphoric Acid SCHEMBL22 0.65
Phosphoric Acid SCHEMBL897840 0.65 CA2 (0.56) LMNAFDPSPGK1PGK2CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8288545-B2 Reactive pyrophosphoric and bisphosphonic acid derivatives and methods of their use GLSYNTHESIS INC. (US) 2012-10-16 US claimed
US-20090299048-A1 REACTIVE PYROPHOSPHORIC AND BISPHOSPHONIC ACID DERIVATIVES AND METHODS OF THEIR USE GLSYNTHESIS INC (US) 2009-12-03 US claimed
WO-2008024169-A1 REACTIVE PYROPHOSPHORIC AND BISPHOSPHONIC ACID DERIVATIVES AND METHODS OF THEIR USE GLSYNTHESIS, INC. (US) 2008-02-28 WO claimed
US-4188234-A STABILIZATION OF VINYL POLYMERS, POLYPHOSPHONIC ACID CHELATING AGENT, PROTECTIVE COATINGS PLAINS CHEMICAL DEVELOPMENT CO. (US) 1980-02-12 US claimed
US-4116990-A OF NON-ALKALI METAL IONS WITH PHOSPHORUS CHELATING COMPOUND PLAINS CHEMICAL DEVELOPMENT CO. (US) 1978-09-26 US claimed
EP-3504356-B1 ALKALINE COMPOSITION FOR TREATING METAL SUBSTARTES PPG IND OHIO INC (US) 2024-08-21 EP disclosed
US-11518960-B2 Alkaline molybdenum cation and phosphonate-containing cleaning composition PPG INDUSTRIES OHIO, INC. (US) 2022-12-06 US disclosed
US-11317632-B2 Materials amd methods for buffering active chlorine solutions PHARMOCON LLC (US) 2022-05-03 US disclosed
CN-110545666-A Materials and methods for buffering active chlorine solutions PHARMOCON LLC 2019-12-06 CN disclosed
EP-3568017-A1 MATERIALS AND METHODS FOR BUFFERING ACTIVE CHLORINE SOLUTIONS Pharmocon LLC (US) 2019-11-20 EP disclosed
US-20190320658-A1 MATERIALS AMD METHODS FOR BUFFERING ACTIVE CHLORINE SOLUTIONS PHARMOCON LLC (US) 2019-10-24 US disclosed
EP-3504356-A1 ALKALINE COMPOSITION FOR TREATING METAL SUBSTRATES PPG Industries Ohio, Inc. (US) 2019-07-03 EP disclosed
EP-2364086-A1 NOVEL ANTITHROMBOTIC DIADENOSINE TETRAPHOSPHATES AND RELATED ANALOGS Glsynthesis Inc. (US) 2011-09-14 EP disclosed
WO-2010059215-A1 NOVEL ANTITHROMBOTIC DIADENOSINE TETRAPHOSPHATES AND RELATED ANALOGS GLSYNTHESIS INC. (US) 2010-05-27 WO disclosed
US-4579720-A USING HYDROXYMETHANE DIPHOSPHONIC ACID PLAINS CHEMICAL DEVELOPMENT CO. (US) 1986-04-01 US disclosed
US-4440646-A HYDROXY OR HALOALKANEPHOSPHONATES PLAINS CHEMICAL DEVELOPMENT CO. (US) 1984-04-03 US disclosed
US-4222995-A ZEOLITE MOLECULAR SIEVES, HYDROTHERMAL CRYSTALLIZATION, ACIDIFICATION, DRYING, COMMINUTION DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) 1980-09-16 US disclosed
US-4188234-A STABILIZATION OF VINYL POLYMERS, POLYPHOSPHONIC ACID CHELATING AGENT, PROTECTIVE COATINGS PLAINS CHEMICAL DEVELOPMENT CO. (US) 1980-02-12 US disclosed
US-4116990-A OF NON-ALKALI METAL IONS WITH PHOSPHORUS CHELATING COMPOUND PLAINS CHEMICAL DEVELOPMENT CO. (US) 1978-09-26 US disclosed
US-4020091-A TIN SALTS OF POLYPHOSPHONIC ACIDS PLAINS CHEMICAL DEVELOPMENT CO. (US) 1977-04-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190320658-A1 MATERIALS AMD METHODS FOR BUFFERING ACTIVE CHLORINE SOLUTIONS LPO, HAO2, CAT LMNA 2725/4885FDPS 4799/4885PGK1 4069/4885
US-11317632-B2 Materials amd methods for buffering active chlorine solutions LPO, HAO2, CAT LMNA 2725/4885FDPS 4799/4885PGK1 4069/4885
US-20090299048-A1 REACTIVE PYROPHOSPHORIC AND BISPHOSPHONIC ACID DERIVATIVES AND METHODS OF THEIR USE PPA1, PPIP5K2, ITPA LMNA 2860/4885FDPS 66/4885PGK1 386/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.