Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 18/20 | 0.44 |
| ▸ | CTSL | P07711 | 17/20 | 0.44 |
| ▸ | CTSS | P25774 | 16/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CTSV | O60911 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4310587 | 0.81 | CTSK (0.47) | CTSKCTSLCTSSCTSVCTSB | |
| SCHEMBL8339896 | 0.81 | CTSK (0.47) | CTSKCTSLCTSSCTSVCTSB | |
| SCHEMBL8337761 | 0.81 | SMYD3 (0.42) | CTSKCTSLCTSSAKR1C3ALOX15 | |
| SCHEMBL5983025 | 0.75 | SMYD3 (0.41) | CTSKCTSLCTSSAKR1C3ALOX15 | |
| SCHEMBL4623836 | 0.73 | SMYD3 (0.41) | CTSKCTSLCTSSCTSVCTSB | |
| SCHEMBL4316021 | 0.73 | SMYD3 (0.41) | CTSKCTSLCTSSCTSVCTSB | |
| SCHEMBL4309590 | 0.73 | SMYD3 (0.41) | CTSKCTSLCTSSCTSVCTSB | |
| SCHEMBL6559920 | 0.73 | PKM (0.44) | CTSKCTSLCTSSCTSB | |
| SCHEMBL4315123 | 0.71 | CTSK (0.58) | CTSKCTSLCTSSCTSVCTSB | |
| SCHEMBL4622098 | 0.71 | ELOVL6 (0.39) | CTSKCTSLCTSSAKR1C3CTSV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004017911-A2 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-03-04 | — | — | WO | disclosed |