Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | JAK3 | P52333 | 1/20 | 0.45 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | NPY1R | P25929 | 1/20 | 0.44 |
| ▸ | NPY2R | P49146 | 1/20 | 0.44 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8934707 | 0.90 | SMN1; SMN2 (0.49) | MEN1KMT2AMAPTLMNANPSR1 | |
| SCHEMBL4809461 | 0.78 | MEN1 (0.57) | MEN1KMT2AMAPTLMNANPSR1 | |
| SCHEMBL25026229 | 0.77 | ALDH1A1 (0.55) | MEN1KMT2ALMNAROCK1NOTUM | |
| SCHEMBL10621398 | 0.75 | ROCK1 (0.54) | MEN1KMT2AMAPTLMNAGAA | |
| SCHEMBL11880068 | 0.75 | ROCK1 (0.50) | MEN1KMT2AMAPTROCK1NOTUM | |
| SCHEMBL17179753 | 0.75 | SMN1; SMN2 (0.48) | MEN1KMT2AMAPTLMNAGAA | |
| SCHEMBL2201933 | 0.75 | SMN1; SMN2 (0.53) | MEN1KMT2AMAPTROCK1NOTUM | |
| SCHEMBL8332339 | 0.75 | ROCK1 (0.50) | MEN1KMT2ALMNAROCK1NOTUM | |
| SCHEMBL24286724 | 0.74 | ALDH1A1 (0.58) | MEN1KMT2AMAPTNPSR1ROCK1 | |
| SCHEMBL23864705 | 0.73 | DRD2 (0.47) | MAPTROCK1NOTUMJAK2JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999002145-A1 | COMBINATION DRUG THERAPIES COMPRISING AMINOGLYCOSIDE ANTIBIOTICS AND N,N'-DISUBSTITUTED GUANIDINES | CAMBRIDGE NEUROSCIENCE, INC. (US) | 1999-01-21 | — | — | WO | disclosed |