Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | CDK4 | P11802 | 1/20 | 0.43 |
| ▸ | CCND1 | P24385 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8334755 | 0.90 | MEN1 (0.46) | SMN1; SMN2ATMALDH1A1MEN1KMT2A | |
| SCHEMBL25026229 | 0.87 | ALDH1A1 (0.55) | SMN1; SMN2ALDH1A1MEN1KMT2ASRD5A1 | |
| SCHEMBL17179753 | 0.84 | SMN1; SMN2 (0.48) | SMN1; SMN2ALDH1A1MEN1KMT2ASRD5A1 | |
| SCHEMBL5923921 | 0.75 | ALDH1A1 (0.49) | SMN1; SMN2ALDH1A1MEN1KMT2ASRD5A1 | |
| SCHEMBL17074033 | 0.75 | SMN1; SMN2 (0.46) | SMN1; SMN2ALDH1A1MEN1KMT2ASRD5A1 | |
| SCHEMBL8938754 | 0.73 | LMNA (0.53) | SMN1; SMN2ALDH1A1MEN1KMT2ASRD5A1 | |
| SCHEMBL12307044 | 0.73 | SMN1; SMN2 (0.54) | SMN1; SMN2ALDH1A1MEN1KMT2ASRD5A1 | |
| SCHEMBL19025755 | 0.72 | SMN1; SMN2 (0.47) | SMN1; SMN2ALDH1A1MEN1KMT2ASRD5A1 | |
| SCHEMBL31092800 | 0.72 | HPGD (0.56) | SMN1; SMN2ATMALDH1A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL10547839 | 0.72 | MAPK1 (0.51) | SMN1; SMN2ALDH1A1MEN1KMT2ASRD5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996030014-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1996-10-03 | — | — | WO | disclosed |