Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.32 |
| ▸ | MEN1 | O00255 | 5/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | CASP1 | P29466 | 3/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.31 |
| ▸ | MTOR | P42345 | 2/20 | 0.31 |
| ▸ | CASP7 | P55210 | 2/20 | 0.31 |
| ▸ | CTSS | P25774 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 2/20 | 0.31 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
| ▸ | IDH1 | O75874 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6267733 | 0.82 | KDM4E (0.32) | ALDH1A1MEN1KMT2AMAPTNPSR1 | |
| SCHEMBL6327028 | 0.82 | L3MBTL1 (0.38) | ALDH1A1TSHRL3MBTL1KDM4ELMNA | |
| SCHEMBL6323174 | 0.82 | USP2 (0.36) | MEN1KMT2APIK3CAMTORUSP2 | |
| SCHEMBL8334943 | 0.81 | USP2 (0.36) | PIK3CAMTORUSP2SMN1; SMN2PIK3R1 | |
| SCHEMBL5847975 | 0.81 | GPR119 (0.32) | ALDH1A1MEN1KMT2AMAPTNPSR1 | |
| SCHEMBL6318463 | 0.77 | USP2 (0.40) | PIK3CAMTORUSP2SMN1; SMN2PIK3R1 | |
| SCHEMBL21314483 | 0.73 | ITGAV (0.37) | MEN1KMT2AMAPTNPSR1KDM4E | |
| SCHEMBL29702161 | 0.71 | ITGAV (0.39) | MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL21314420 | 0.71 | ITGAV (0.39) | MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL30474571 | 0.70 | ALDH1A1 (0.39) | ALDH1A1L3MBTL1KDM4ESMN1; SMN2GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004058254-A1 | HETEROARYLALKANOIC ACIDS AS INTEGRIN RECEPTOR ANTAGONISTS | PHARMACIA CORPORATION (US) | 2004-07-15 | — | — | WO | disclosed |