⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL260075 | 0.78 | — | — | |
| SCHEMBL31331896 | 0.75 | — | — | |
| SCHEMBL14890587 | 0.75 | LMNA (0.42) | — | |
| SCHEMBL1401066 | 0.73 | MGAM (0.45) | — | |
| SCHEMBL10389469 | 0.71 | MGAM (0.56) | — | |
| SCHEMBL1608 | 0.71 | — | — | |
| SCHEMBL2128645 | 0.71 | MGAM (0.56) | — | |
| SCHEMBL16923813 | 0.71 | — | — | |
| SCHEMBL71051 | 0.71 | — | — | |
| SCHEMBL12239877 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004060890-A1 | 2-OXOPYRIDIN-3-YL THIA (DI) AZOLE DERIVATES FOR USE IN THE TREATMENT OF CELL PROLIFERATION AND APOPTOSIS RELATED DISEASES | AMGEN INC. (US) | 2004-07-22 | — | — | WO | disclosed |