Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 3/20 | 0.38 |
| ▸ | TDO2 | P48775 | 3/20 | 0.38 |
| ▸ | MLKL | Q8NB16 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11500414 | 0.89 | LMNA (0.46) | MEN1KMT2ANPSR1KDM4ELMNA | |
| SCHEMBL6670224 | 0.89 | SCN1A (0.42) | KDM4ELMNASMN1; SMN2TSHRIDO1 | |
| SCHEMBL8111645 | 0.82 | IDO1 (0.60) | MEN1KMT2ANPSR1LMNASMN1; SMN2 | |
| SCHEMBL10683339 | 0.79 | CHRNA7 (0.52) | MEN1KMT2ANPSR1KDM4ECHRNA7 | |
| SCHEMBL13697238 | 0.78 | MLKL (0.51) | MEN1KMT2ANPSR1KDM4ELMNA | |
| SCHEMBL11781680 | 0.77 | KDM4E (0.46) | MEN1KMT2ANPSR1KDM4ELMNA | |
| SCHEMBL3482548 | 0.77 | MEN1 (0.43) | MEN1KMT2ANPSR1KDM4ELMNA | |
| SCHEMBL14380217 | 0.77 | MEN1 (0.43) | MEN1KMT2ANPSR1KDM4ELMNA | |
| SCHEMBL98113 | 0.77 | IDO1 (0.64) | IDO1TDO2 | |
| SCHEMBL21382043 | 0.77 | SCN1A (0.37) | KDM4ELMNASMN1; SMN2TSHRIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998052898-A9 | PHARMACEUTICAL AGENTS FOR THE TREATMENT OF CEREBRAL AMYLOIDOSIS | NYMOX CORP (CA) | 1999-04-01 | — | — | WO | disclosed |