Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.48 |
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SLC6A15 | Q9H2J7 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HRH2 | P25021 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | MMP7 | P09237 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL304030 | 0.79 | LIPE (0.41) | GPR119SLC6A15FAAHHRH2HRH1 | |
| SCHEMBL14434131 | 0.78 | CHRNA7 (0.44) | CHRNA7GAASLC6A15ALDH1A1LMNA | |
| SCHEMBL26317513 | 0.78 | TSHR (0.43) | GPR119GAAFAAHALDH1A1HRH2 | |
| SCHEMBL27979621 | 0.78 | — | — | |
| SCHEMBL14434126 | 0.76 | ALDH1A1 (0.52) | GAAALDH1A1LMNA | |
| SCHEMBL417717 | 0.75 | USP2 (0.51) | GPR119ALDH1A1LMNA | |
| SCHEMBL2654623 | 0.74 | TSHR (0.40) | GPR119FAAHALDH1A1LMNAHRH2 | |
| SCHEMBL5412873 | 0.74 | ALDH1A1 (0.42) | GPR119GAAFAAHALDH1A1 | |
| SCHEMBL7381267 | 0.73 | ABHD6 (0.38) | GPR119SLC6A15GRM5GRM1 | |
| SCHEMBL12283406 | 0.72 | ALDH1A1 (0.45) | GPR119GAAALDH1A1LMNAMMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004101558-A1 | 2-IMIDAZO-BENZOTHIAZOLES AS ADENOSINE RECEPTOR LIGANDS | F. HOFFMANN-LA ROCHE AG (CH) | 2004-11-25 | — | — | WO | disclosed |