Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 18/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7152117 | 0.87 | CYP1A2 (0.41) | KCNH2CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL936173 | 0.77 | — | — | |
| SCHEMBL19206141 | 0.77 | — | — | |
| SCHEMBL9242 | 0.77 | — | — | |
| SCHEMBL465303 | 0.77 | HSD17B10 (0.44) | KCNH2CHRM2CHRM1 | |
| SCHEMBL1404003 | 0.75 | ALDH1A1 (0.43) | KCNH2CHRM2CHRM1 | |
| SCHEMBL7704607 | 0.75 | MAPT (0.35) | — | |
| SCHEMBL27813443 | 0.74 | PAOX (0.41) | KCNH2CHRM2CHRM1 | |
| Hydrochloric Acid SCHEMBL29203168 | 0.74 | PAOX (0.41) | KCNH2CHRM2CHRM1 | |
| SCHEMBL27813421 | 0.74 | PAOX (0.41) | KCNH2CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915826-A4 | SMOOTH MUSCLE SPASMOLYTIC AGENTS, COMPOSITIONS AND METHODS OF USE THEREOF | BRIDGE PHARMA INC (US) | 1999-12-29 | — | — | EP | disclosed |
| EP-0915826-A1 | SMOOTH MUSCLE SPASMOLYTIC AGENTS, COMPOSITIONS AND METHODS OF USE THEREOF | Bridge Pharma, Inc. (US) | 1999-05-19 | — | — | EP | disclosed |
| WO-1998000390-A1 | SMOOTH MUSCLE SPASMOLYTIC AGENTS, COMPOSITIONS AND METHODS OF USE THEREOF | BRIDGE PHARMA, INC. (US) | 1998-01-08 | — | — | WO | disclosed |