Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1404043 | 0.92 | SMN1; SMN2 (0.46) | ALDH1A1SMN1; SMN2HSD17B10CYP1A2CYP2C9 | |
| SCHEMBL465303 | 0.92 | HSD17B10 (0.44) | ALDH1A1SMN1; SMN2HSD17B10CYP1A2CYP2C9 | |
| SCHEMBL27956502 | 0.90 | LMNA (0.48) | ALDH1A1SMN1; SMN2HSD17B10CYP1A2CYP2C9 | |
| SCHEMBL865665 | 0.90 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2HSD17B10CYP1A2CYP2C9 | |
| SCHEMBL465473 | 0.89 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2HSD17B10HIF1ALMNA | |
| SCHEMBL557366 | 0.89 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2HSD17B10HIF1ALMNA | |
| SCHEMBL3429982 | 0.86 | CYP1A2 (0.52) | ALDH1A1SMN1; SMN2HSD17B10CYP1A2CYP2C9 | |
| SCHEMBL11713997 | 0.86 | HSD17B10 (0.41) | ALDH1A1SMN1; SMN2HSD17B10CYP1A2CYP2C9 | |
| SCHEMBL3427325 | 0.86 | HSD17B10 (0.41) | ALDH1A1SMN1; SMN2HSD17B10CYP1A2CYP2C9 | |
| SCHEMBL5052250 | 0.86 | SMN1; SMN2 (0.43) | ALDH1A1SMN1; SMN2HSD17B10CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1399409-B1 | METHOD FOR PRODUCING (METH)ACRYLIC ACID ESTERS | BASF SE (DE) | 2012-10-31 | — | — | EP | claimed |
| US-8029752-B2 | Approach in controlling DSP scale in bayer process | NALCO COMPANY (US) | 2011-10-04 | — | — | US | claimed |
| WO-2010117949-A2 | NOVEL APPROACH IN CONTROLLING DSP SCALE IN THE BAYER PROCESS | NALCO COMPANY (US) | 2010-10-14 | — | — | WO | claimed |
| US-20100254866-A1 | NOVEL APPROACH IN CONTROLLING DSP SCALE IN BAYER PROCESS | NALCO COMPANY | 2010-10-07 | — | — | US | claimed |
| CN-100349854-C | Method for producing (meth) acrylic acid esters | BASF AG (DE) | 2007-11-21 | — | — | CN | claimed |
| US-7268251-B2 | Method for producing (meth) acrylic acid esters | BASF AKTIENGESELLSCHAFT (DE) | 2007-09-11 | — | — | US | claimed |
| US-7026503-B2 | Method for producing (meth)acrylic acid esters | BASF AKTIENGESELLSCHAFT (DE) | 2006-04-11 | — | — | US | claimed |
| EP-1399408-B1 | METHOD FOR PRODUCING (METH)ACRYLIC ACID ESTERS | BASF AG (DE) | 2006-03-22 | — | — | EP | claimed |
| US-10174349-B2 | Recombinant cell producing 2-hydroxyisobutyric acid | EVONIK ROEHM GMBH (DE) | 2019-01-08 | — | — | US | disclosed |
| EP-2291530-B1 | RECOMBINANT CELL PRODUCING 2-HYDROXYISOBUTYRIC ACID | EVONIK ROEHM GMBH (DE) | 2018-12-26 | — | — | EP | disclosed |
| US-20180000816-A1 | Use of a Heterocyclic Bcl-xL Inhibitor and Related Analogs for Removing Senescent Cells in the Treatment of Eye Diseases and Other Age-Related Conditions | UNITY BIOTECHNOLOGY, INC. | 2018-01-04 | — | — | US | disclosed |
| CN-107083352-A | Produce the recombinant cell of 2 hydroxy-iso-butyric acids | 赢创罗姆有限公司 | 2017-08-22 | — | — | CN | disclosed |
| WO-2017032699-A1 | METHOD FOR PRODUCING LOW-BOILING (METH)ACRYLIC ACID ESTERS | BASF SE (DE) | 2017-03-02 | — | — | WO | disclosed |
| US-20150258068-A1 | COMBINATION THERAPIES | MEI PHARMA, INC. | 2015-09-17 | — | — | US | disclosed |
| WO-2003099253-A1 | PERSONAL CARE COMPOSITIONS WITH HYDROXY AMINE NEUTRALIZED POLYMERS | UNILEVER PLC (GB) | 2003-12-04 | — | — | WO | disclosed |
| WO-2003099252-A1 | COSMETIC COMPOSITIONS WITH HYDROXY AMINE SALTS OF MALONIC ACID | UNILEVER PLC (GB) | 2003-12-04 | — | — | WO | disclosed |
| US-20030224023-A1 | Cosmetic compositions with hydroxy amine salts of malonic acid | UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. | 2003-12-04 | — | — | US | disclosed |
| EP-0838508-B1 | Aqueous ink composition for use in an ink-jet printer | SEIKO EPSON CORP (JP) | 2001-08-29 | — | — | EP | disclosed |
| US-5871572-A | COLORANT, WATER, A WATER-SOLUBLE ORGANIC SOLVENT, AND PECTIC ACID | SEIKO EPSON CORPORATION (JP) | 1999-02-16 | — | — | US | disclosed |
| EP-0838508-A2 | Aqueous ink composition for use in an ink-jet printer | SEIKO EPSON CORPORATION (JP) | 1998-04-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030224023-A1 | Cosmetic compositions with hydroxy amine salts of malonic acid | CUTA, TYR, DDC | ALDH1A1 281/4885SMN1; SMN2 3395/4885HSD17B10 413/4885 |
| US-20180000816-A1 | Use of a Heterocyclic Bcl-xL Inhibitor and Related Analogs for Removing Senescent Cells in the Treatment of Eye Diseases and Other Age-Related Conditions | BCL2L1, BCL2, BCL2L13 | ALDH1A1 3458/4885SMN1; SMN2 2667/4885HSD17B10 4260/4885 |
| US-20150258068-A1 | COMBINATION THERAPIES | HDAC1, HDAC8, HDAC5 | ALDH1A1 701/4885SMN1; SMN2 1378/4885HSD17B10 3147/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.