SCHEMBL8335371

SCHEMBL8335371

O=C1CNC(=S)[N+]1(c1ccccc1)c1ccccc1

nearest known ligand 0.31

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.31
GAA P10253 1/20 0.31
MAPT P10636 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
CA12 O43570 1/20 0.31
CA9 Q16790 1/20 0.31
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30
HPGD P15428 1/20 0.30
GSK3A P49840 1/20 0.30
GSK3B P49841 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7615549 0.80 CA12 (0.32) CA12CA9HPGDGSK3AGSK3B
SCHEMBL3322196 0.65 GSK3A (0.34) KDM4EGAAMAPTTDP1GSK3A
SCHEMBL7625905 0.62 MEN1 (0.33) TDP1MEN1KMT2AGSK3AGSK3B
SCHEMBL3257579 0.60 LMNA (0.32) GAAHPGD
SCHEMBL11001347 0.59 CYP1A2 (0.31) KMT2A
SCHEMBL9717994 0.58 MEN1 (0.41) KDM4EMAPTTDP1CA9MEN1
SCHEMBL8341767 0.57
SCHEMBL9070050 0.56 KDM4E (0.30) KDM4EGSK3B
SCHEMBL8881696 0.54 ALDH1A1 (0.38) MAPTTDP1CA12CA9GSK3B
Aniline SCHEMBL6921161 0.54 TSHR (0.58) KDM4EMAPTTDP1CA12CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0929840-A1 SILVER HALIDE LIGHT SENSITIVE EMULSION LAYER HAVING ENHANCED PHOTOGRAPHIC SENSITIVITY EASTMAN KODAK COMPANY (US) 1999-07-21 EP disclosed
WO-1999005570-A1 SILVER HALIDE LIGHT SENSITIVE EMULSION LAYER HAVING ENHANCED PHOTOGRAPHIC SENSITIVITY EASTMAN KODAK COMPANY (US) 1999-02-04 WO disclosed