Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | HTR1B | P28222 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | DRD1 | P21728 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8338047 | 0.88 | ALDH1A1 (0.66) | MEN1KMT2AALDH1A1KDM4EPOLB | |
| SCHEMBL2804626 | 0.83 | DRD2 (0.54) | MEN1KMT2AKDM4EGAADRD2 | |
| SCHEMBL8338923 | 0.81 | ALDH1A1 (0.58) | ALDH1A1KDM4EPOLBTDP1MAPT | |
| SCHEMBL876068 | 0.81 | DRD2 (0.69) | MEN1KMT2AKDM4EGAATDP1 | |
| SCHEMBL8334830 | 0.81 | KMT2A (0.49) | MEN1KMT2AALDH1A1KDM4EPOLB | |
| SCHEMBL27040260 | 0.78 | HTR1B (0.75) | MEN1KMT2AALDH1A1KDM4EGAA | |
| SCHEMBL16997486 | 0.78 | PTGDR2 (0.48) | MEN1KMT2AALDH1A1KDM4EPOLB | |
| SCHEMBL2322967 | 0.78 | HTR1B (0.67) | MEN1KMT2AALDH1A1KDM4EGAA | |
| SCHEMBL226018 | 0.77 | LTA4H (0.60) | MEN1KMT2AALDH1A1KDM4EGAA | |
| SCHEMBL227430 | 0.77 | LTA4H (0.60) | MEN1KMT2AALDH1A1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004014844-A2 | ARYL AND HETEROARYL COMPOUNDS AND METHODS TO MODULATE COAGULATION | TRANSTECH PHARMA, INC. (US) | 2004-02-19 | — | — | WO | disclosed |