Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29515039 | 1.00 | KDM4E (0.36) | KDM4EGAAKMT2AMEN1USP2 | |
| SCHEMBL5047321 | 0.72 | — | — | |
| SCHEMBL4838387 | 0.70 | HTR2A (0.36) | KMT2AMEN1USP2HTR2AALOX15 | |
| SCHEMBL7518490 | 0.70 | LMNA (0.39) | SMN1; SMN2TSHRLMNAMAPK1SCN4A | |
| SCHEMBL19976713 | 0.65 | KEAP1 (0.36) | KDM4EGAAKMT2AMEN1USP2 | |
| SCHEMBL12175881 | 0.63 | CES1 (0.39) | KDM4EGAAKMT2AMEN1HTT | |
| SCHEMBL19438835 | 0.62 | TLR9 (0.40) | KDM4EGAAKMT2AMEN1USP2 | |
| SCHEMBL5894079 | 0.62 | TLR9 (0.35) | KDM4EGAAKMT2AMEN1TLR9 | |
| SCHEMBL25058991 | 0.61 | MAOA (0.48) | KDM4EGAAKMT2AMEN1USP2 | |
| SCHEMBL12175889 | 0.61 | LMNA (0.52) | GAAHTR2ASMN1; SMN2TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999009845-A1 | IMIDAZOQUINOXALINE PROTEIN TYROSINE KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-03-04 | — | — | WO | claimed |
| CN-111808109-B | Pyridazine quinoxaline diamine Schiff base cobalt ion fluorescent probe and preparation method thereof | 南京林业大学 | 2022-03-25 | — | — | CN | disclosed |
| CN-111808109-A | Pyridazine quinoxaline diamine Schiff base cobalt ion fluorescent probe and preparation method thereof | 南京林业大学 | 2020-10-23 | — | — | CN | disclosed |
| EP-3185325-A1 | ORGANIC LIGHT-EMITTING DEVICE | Samsung Display Co., Ltd. (KR) | 2017-06-28 | — | — | EP | disclosed |
| WO-1999009845-A1 | IMIDAZOQUINOXALINE PROTEIN TYROSINE KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-03-04 | — | — | WO | disclosed |