Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | MMP8 | P22894 | 1/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | CTSS | P25774 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.47 |
| ▸ | TACR1 | P25103 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | F10 | P00742 | 2/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13953995 | 0.88 | SMN1; SMN2 (0.47) | MMP2MMP9MMP8CYP2A6CTSL | |
| SCHEMBL21263556 | 0.87 | MMP2 (0.48) | MMP2MMP9MMP8CYP2A6CTSL | |
| SCHEMBL12727418 | 0.86 | MMP2 (0.52) | MMP2MMP9MMP8CYP2A6CTSL | |
| SCHEMBL805209 | 0.86 | MMP2 (0.52) | MMP2MMP9MMP8CYP2A6CTSL | |
| SCHEMBL20976930 | 0.86 | MMP2 (0.52) | MMP2MMP9MMP8CYP2A6CTSL | |
| SCHEMBL14048310 | 0.86 | MMP2 (0.52) | MMP2MMP9MMP8CYP2A6CTSL | |
| SCHEMBL16203423 | 0.86 | MMP2 (0.52) | MMP2MMP9MMP8CYP2A6CTSL | |
| SCHEMBL24511005 | 0.85 | MMP2 (0.54) | MMP2MMP9MMP8CYP2A6CTSL | |
| SCHEMBL16572507 | 0.81 | OPRD1 (0.53) | MMP2MMP9MMP8CYP2A6CTSL | |
| SCHEMBL25029777 | 0.78 | CYP2A6 (0.53) | MMP2MMP9MMP8CYP2A6SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011115871-A1 | PHARMACEUTICAL COMPOSITIONS OF GROWTH HORMONE SECRETAGOGUE RECEPTOR LIGANDS | IPSEN PHARMA S.A.S. (FR) | 2011-09-22 | — | — | WO | disclosed |
| EP-2130548-A2 | Growth Hormone Releasing Peptides | IPSEN PHARMA (FR) | 2009-12-09 | — | — | EP | disclosed |
| EP-1542716-B1 | GROWTH HORMONE RELEASING PEPTIDES | IPSEN PHARMA (FR) | 2009-11-04 | — | — | EP | disclosed |
| WO-2004014415-A1 | GROWTH HORMONE RELEASING PEPTIDES | SOCIETE DE CONSEIL DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES, S.A.S. (FR) | 2004-02-19 | — | — | WO | disclosed |