Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 18/20 | 0.70 |
| ▸ | HTR1B | P28222 | 18/20 | 0.70 |
| ▸ | HTR1A | P08908 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8151636 | 0.83 | HTR1D (1.00) | HTR1DHTR1B | |
| SCHEMBL8805258 | 0.81 | HTR1D (0.70) | HTR1DHTR1BHTR1A | |
| SCHEMBL8333324 | 0.80 | HTR1D (0.63) | HTR1DHTR1BHTR1A | |
| SCHEMBL9047205 | 0.76 | HTR1A (0.85) | HTR1DHTR1BHTR1A | |
| SCHEMBL8984395 | 0.76 | HTR1D (0.87) | HTR1DHTR1B | |
| SCHEMBL1377300 | 0.76 | HTR1A (0.83) | HTR1DHTR1BHTR1A | |
| SCHEMBL30468393 | 0.74 | HTR1A (0.67) | HTR1DHTR1BHTR1A | |
| SCHEMBL17249759 | 0.74 | HTR1A (0.67) | HTR1DHTR1BHTR1A | |
| SCHEMBL739944 | 0.73 | HTR1A (0.79) | HTR1DHTR1BHTR1A | |
| SCHEMBL28178875 | 0.72 | HTR1A (0.76) | HTR1DHTR1BHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5981529-A | Substituted indolylpropyl-piperazine derivatives as 5-HT1D α agonists | MERCK SHARP & DOHME LIMITED (GB) | 1999-11-09 | — | — | US | disclosed |