Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 2/20 | 0.53 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.53 |
| ▸ | ADH5 | P11766 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.46 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.46 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.44 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.44 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25442242 | 0.83 | CYP11B1 (0.51) | CYP11B1CYP11B2CYP19A1ADH5LMNA | |
| SCHEMBL12990375 | 0.83 | NOTUM (0.53) | CYP11B1CYP11B2CYP19A1ADH5LMNA | |
| SCHEMBL22214035 | 0.83 | ENPP2 (0.53) | CYP11B1CYP11B2CYP19A1ADH5LMNA | |
| SCHEMBL12117429 | 0.81 | CYP11B1 (0.56) | CYP11B1CYP11B2CYP19A1ADH5LMNA | |
| SCHEMBL25442434 | 0.79 | CYP19A1 (0.48) | CYP11B1CYP11B2CYP19A1ADH5LMNA | |
| SCHEMBL8338440 | 0.77 | NOTUM (0.58) | CYP11B1CYP11B2CYP19A1ADH5LMNA | |
| SCHEMBL28366763 | 0.77 | ENPP2 (0.58) | CYP11B1CYP11B2CYP19A1ADH5LMNA | |
| SCHEMBL993223 | 0.77 | LMNA (0.58) | CYP11B1CYP11B2CYP19A1ADH5LMNA | |
| SCHEMBL18101813 | 0.74 | CYP11B1 (0.59) | CYP11B1CYP11B2CYP19A1ADH5LMNA | |
| SCHEMBL801703 | 0.74 | NOTUM (0.63) | CYP11B1CYP11B2CYP19A1ADH5LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999009845-A1 | IMIDAZOQUINOXALINE PROTEIN TYROSINE KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-03-04 | — | — | WO | claimed |