Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.78 |
| ▸ | SYK | P43405 | 1/20 | 0.75 |
| ▸ | MEN1 | O00255 | 5/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | MAPT | P10636 | 4/20 | 0.62 |
| ▸ | RECQL | P46063 | 3/20 | 0.62 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 4/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.59 |
| ▸ | EIF4E | P06730 | 1/20 | 0.59 |
| ▸ | EIF4G1 | Q04637 | 1/20 | 0.59 |
| ▸ | THRB | P10828 | 1/20 | 0.59 |
| ▸ | MAP3K5 | Q99683 | 7/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4402019 | 0.88 | ENPP2 (1.00) | ENPP2SYKMEN1KMT2AALDH1A1 | |
| SCHEMBL4398637 | 0.88 | ENPP2 (1.00) | ENPP2SYKMEN1KMT2AALDH1A1 | |
| SCHEMBL30774050 | 0.85 | SYK (1.00) | ENPP2SYKMEN1KMT2AALDH1A1 | |
| SCHEMBL1135868 | 0.85 | SYK (1.00) | ENPP2SYKMEN1KMT2AALDH1A1 | |
| SCHEMBL12668370 | 0.85 | SYK (1.00) | ENPP2SYKMEN1KMT2AALDH1A1 | |
| SCHEMBL1135867 | 0.85 | SYK (1.00) | ENPP2SYKMEN1KMT2AALDH1A1 | |
| SCHEMBL3897828 | 0.83 | MAP3K5 (0.78) | ENPP2SYKMEN1KMT2AALDH1A1 | |
| SCHEMBL3897831 | 0.83 | MAP3K5 (0.78) | ENPP2SYKMEN1KMT2AALDH1A1 | |
| SCHEMBL3132334 | 0.80 | MAPT (0.73) | ENPP2SYKMEN1KMT2AALDH1A1 | |
| SCHEMBL3132328 | 0.80 | MAPT (0.73) | ENPP2SYKMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004043955-A1 | RHODANINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | RIGEL PHARMACEUTICALS, INC. (US) | 2004-05-27 | — | — | WO | disclosed |