Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 7/20 | 0.50 |
| ▸ | TUBB | P07437 | 7/20 | 0.50 |
| ▸ | TUBA3C | P0DPH7 | 7/20 | 0.50 |
| ▸ | TUBA1B | P68363 | 7/20 | 0.50 |
| ▸ | TUBA4A | P68366 | 7/20 | 0.50 |
| ▸ | TUBB4B | P68371 | 7/20 | 0.50 |
| ▸ | TUBB3 | Q13509 | 7/20 | 0.50 |
| ▸ | TUBB2A | Q13885 | 7/20 | 0.50 |
| ▸ | TUBB8 | Q3ZCM7 | 7/20 | 0.50 |
| ▸ | TUBA3E | Q6PEY2 | 7/20 | 0.50 |
| ▸ | TUBA1A | Q71U36 | 7/20 | 0.50 |
| ▸ | TUBA1C | Q9BQE3 | 7/20 | 0.50 |
| ▸ | TUBB6 | Q9BUF5 | 7/20 | 0.50 |
| ▸ | TUBB2B | Q9BVA1 | 7/20 | 0.50 |
| ▸ | TUBB1 | Q9H4B7 | 7/20 | 0.50 |
| ▸ | TPMT | P51580 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2733211 | 0.87 | PTGS2 (0.59) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL8339781 | 0.85 | AKR1B1 (0.50) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL8339208 | 0.81 | AKR1B1 (0.49) | MAPT | |
| SCHEMBL29286367 | 0.79 | TUBB4A (0.74) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL30079962 | 0.79 | TUBB4A (0.74) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL3364601 | 0.79 | TUBB4A (0.54) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL8372028 | 0.79 | PTGS2 (0.73) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL14882656 | 0.79 | MAPT (0.47) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL8342729 | 0.78 | NPC1 (0.48) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL3566176 | 0.78 | HTR2A (0.53) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004043367-A2 | FUSED HETEROCYCLIC COMPOUNDS AND USE THEREOF | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-05-27 | — | — | WO | disclosed |