Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 6/20 | 0.54 |
| ▸ | TUBB | P07437 | 6/20 | 0.54 |
| ▸ | TUBA3C | P0DPH7 | 6/20 | 0.54 |
| ▸ | TUBA1B | P68363 | 6/20 | 0.54 |
| ▸ | TUBA4A | P68366 | 6/20 | 0.54 |
| ▸ | TUBB4B | P68371 | 6/20 | 0.54 |
| ▸ | TUBB3 | Q13509 | 6/20 | 0.54 |
| ▸ | TUBB2A | Q13885 | 6/20 | 0.54 |
| ▸ | TUBB8 | Q3ZCM7 | 6/20 | 0.54 |
| ▸ | TUBA3E | Q6PEY2 | 6/20 | 0.54 |
| ▸ | TUBA1A | Q71U36 | 6/20 | 0.54 |
| ▸ | TUBA1C | Q9BQE3 | 6/20 | 0.54 |
| ▸ | TUBB6 | Q9BUF5 | 6/20 | 0.54 |
| ▸ | TUBB2B | Q9BVA1 | 6/20 | 0.54 |
| ▸ | TUBB1 | Q9H4B7 | 6/20 | 0.54 |
| ▸ | TPMT | P51580 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11896174 | 0.87 | TDP1 (0.58) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL1122521 | 0.87 | PTGS2 (0.64) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL30079962 | 0.84 | TUBB4A (0.74) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL29286367 | 0.84 | TUBB4A (0.74) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL8372028 | 0.84 | PTGS2 (0.73) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL10285344 | 0.83 | AKR1B1 (0.55) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL3566176 | 0.82 | HTR2A (0.53) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL17655662 | 0.82 | PTGS2 (0.52) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL13952332 | 0.81 | TUBB4A (0.60) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL13535542 | 0.80 | PTGS2 (0.50) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1341503-B1 | AGENT AND METHOD FOR DYEING KERATIN FIBRES | WELLA AG (DE) | 2008-02-13 | — | — | EP | claimed |
| US-6835212-B2 | Compound with a nucleophilic reaction center, aryl alcohol or benzyl alcohol derivatives and an oxidizing enzyme | WELLA AKTIENGESELLSCHAFT (DE) | 2004-12-28 | — | — | US | claimed |
| US-20030041391-A1 | Agent and method for dyeing keratin fibres | Wella GmbH (DE) | 2003-03-06 | — | — | US | claimed |
| US-7649015-B2 | Cellular accumulation of phosphonate analogs of HIV protease inhibitor compounds | GILEAD SCIENCES, INC. (US) | 2010-01-19 | — | — | US | disclosed |
| US-7649015-B2 | Cellular accumulation of phosphonate analogs of HIV protease inhibitor compounds | GILEAD SCIENCES, INC. (US) | 2010-01-19 | — | — | US | disclosed |
| US-7649015-B2 | Cellular accumulation of phosphonate analogs of HIV protease inhibitor compounds | GILEAD SCIENCES, INC. (US) | 2010-01-19 | — | — | US | disclosed |
| EP-1341503-B1 | AGENT AND METHOD FOR DYEING KERATIN FIBRES | WELLA AG (DE) | 2008-02-13 | — | — | EP | disclosed |
| US-20070010489-A1 | Cellular accumulation of phosphonate analogs of hiv protease inhibitor compounds | GILEAD SCIENCES, INC. | 2007-01-11 | — | — | US | disclosed |
| US-20070010489-A1 | Cellular accumulation of phosphonate analogs of hiv protease inhibitor compounds | GILEAD SCIENCES, INC. | 2007-01-11 | — | — | US | disclosed |
| US-20070010489-A1 | Cellular accumulation of phosphonate analogs of hiv protease inhibitor compounds | GILEAD SCIENCES, INC. | 2007-01-11 | — | — | US | disclosed |
| EP-1711617-A1 | METHOD AND COMPOSITIONS FOR IDENTIFYING ANTI-HIV THERAPEUTICS COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2006-10-18 | — | — | EP | disclosed |
| US-6835212-B2 | Compound with a nucleophilic reaction center, aryl alcohol or benzyl alcohol derivatives and an oxidizing enzyme | WELLA AKTIENGESELLSCHAFT (DE) | 2004-12-28 | — | — | US | disclosed |
| EP-1404289-A1 | 1-BENZOPYRANE-DERIVATIVES AND COLOURING AGENTS CONTAINING THE SALTS THEREOF | Wella Aktiengesellschaft (DE) | 2004-04-07 | — | — | EP | disclosed |
| US-20030213071-A1 | 5-Aryl-1.3.3.-trimethyl-2-methylene-indoline derivatives and salts thereof, methods for the production and use of said compounds for the temporary coloration of fibres | Wella GmbH (DE) | 2003-11-20 | — | — | US | disclosed |
| WO-2003090690-A2 | CELLULAR ACCUMULATION OF PHOSPHONATE ANALOGS OF HIV PROTEASE INHIBITOR COMPOUNDS AND THE COMPOUNDS AS SUCH | GILEAD SCIENCES, INC. (US) | 2003-11-06 | — | — | WO | disclosed |
| US-20030196281-A1 | 1-benzopyrane-derivatives and colouring agents containing the salts thereof | WELLA AKTIENGESELLSCHAFT (DE) | 2003-10-23 | — | — | US | disclosed |
| US-20030041391-A1 | Agent and method for dyeing keratin fibres | Wella GmbH (DE) | 2003-03-06 | — | — | US | disclosed |
| EP-1280773-A1 | 5-ARYL-1.3.3.-TRIMETHYL-2-METHYLENE-INDOLINE DERIVATIVES AND SALTS THEREOF, METHODS FOR THE PRODUCTION AND USE OF SAID COMPOUNDS FOR THE TEMPORARY COLORATION OF FIBRES | Wella Aktiengesellschaft (DE) | 2003-02-05 | — | — | EP | disclosed |
| WO-2003000214-A1 | 1-BENZOPYRANE-DERIVATIVES AND COLOURING AGENTS CONTAINING THE SALTS THEREOF | WELLA AKTIENGESELLSCHAFT (DE) | 2003-01-03 | — | — | WO | disclosed |
| WO-2002085854-A1 | 5-ARYL-1.3.3.-TRIMETHYL-2-METHYLENE-INDOLINE DERIVATIVES AND SALTS THEREOF, METHODS FOR THE PRODUCTION AND USE OF SAID COMPOUNDS FOR THE TEMPORARY COLORATION OF FIBRES | WELLA AKTIENGESELLSCHAFT (DE) | 2002-10-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030213071-A1 | 5-Aryl-1.3.3.-trimethyl-2-methylene-indoline derivatives and salts thereof, methods for the production and use of said compounds for the temporary coloration of fibres | INMT, KRT18, IPO5 | TUBB4A 130/4885TUBB 272/4885TUBA3C 177/4885 |
| US-20030196281-A1 | 1-benzopyrane-derivatives and colouring agents containing the salts thereof | KRT18, COL2A1, PHB1 | TUBB4A 583/4885TUBB 488/4885TUBA3C 496/4885 |
| US-20070010489-A1 | Cellular accumulation of phosphonate analogs of hiv protease inhibitor compounds | PPA1, PNP, PPME1 | TUBB4A 1947/4885TUBB 1927/4885TUBA3C 2384/4885 |
| US-20030041391-A1 | Agent and method for dyeing keratin fibres | KRT18, AKR7A2, ADH5 | TUBB4A 16/4885TUBB 17/4885TUBA3C 76/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.