Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.43 |
| ▸ | LMNA | P02545 | 8/20 | 0.43 |
| ▸ | MEN1 | O00255 | 8/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 6/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14667461 | 0.68 | MAPT (0.55) | MAPTLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL13766486 | 0.67 | MAPT (0.44) | MAPTLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL622653 | 0.65 | KDM4E (0.66) | MAPTLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL2554804 | 0.65 | MAPT (0.58) | MAPTLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL2554802 | 0.65 | MAPT (0.58) | MAPTLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL23731503 | 0.63 | TDP1 (0.57) | MAPTMEN1KMT2AALDH1A1TP53 | |
| SCHEMBL8806045 | 0.63 | ALDH1A1 (0.57) | MAPTLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL4459311 | 0.62 | MAPT (0.59) | MAPTLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL12279902 | 0.62 | MAPT (0.71) | MAPTLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL25151642 | 0.62 | MAPT (0.43) | MAPTLMNAMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004043955-A1 | RHODANINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | RIGEL PHARMACEUTICALS, INC. (US) | 2004-05-27 | — | — | WO | disclosed |