Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 12/20 | 0.44 |
| ▸ | MEN1 | O00255 | 8/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.44 |
| ▸ | LMNA | P02545 | 7/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 6/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | KLK7 | P49862 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PHGDH | O43175 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL46214 | 0.80 | TDP1 (0.52) | MAPTMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL21337609 | 0.74 | TDP1 (0.47) | MAPTMEN1KMT2ALMNAHPGD | |
| SCHEMBL46230 | 0.70 | MAPT (0.50) | MAPTMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL8337837 | 0.67 | MAPT (0.43) | MAPTMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL622653 | 0.66 | KDM4E (0.66) | MAPTMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL10118579 | 0.66 | PIK3CA (0.44) | MAPTMEN1KMT2ALMNAKDM4E | |
| SCHEMBL2554804 | 0.66 | MAPT (0.58) | MAPTMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL2554802 | 0.66 | MAPT (0.58) | MAPTMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL3075966 | 0.65 | PHGDH (0.77) | MAPTMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL14667461 | 0.64 | MAPT (0.55) | MAPTMEN1KMT2ALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7566732-B2 | Rhodanine compositions for use as antiviral agents | RIGEL PHARMACEUTICALS, INC. (US) | 2009-07-28 | — | — | US | disclosed |