Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | S100A9 | P06702 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.44 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9996884 | 0.85 | HSD17B10 (0.53) | ALDH1A1KMT2AHTTS100A9POLB | |
| SCHEMBL15055480 | 0.83 | ALDH1A1 (0.49) | ALDH1A1KMT2AHTTS100A9LMNA | |
| SCHEMBL8337897 | 0.81 | CCR2 (0.41) | ALDH1A1KMT2AHTTS100A9LMNA | |
| SCHEMBL8336957 | 0.79 | HSD17B2 (0.38) | ALDH1A1KMT2AHTTS100A9LMNA | |
| SCHEMBL5227907 | 0.77 | ALDH1A1 (0.53) | ALDH1A1KMT2AHTTS100A9LMNA | |
| SCHEMBL16235359 | 0.76 | TSHR (0.62) | ALDH1A1KMT2AHTTS100A9MAPT | |
| SCHEMBL16235366 | 0.76 | ALDH1A1 (0.55) | ALDH1A1KMT2AHTTS100A9LMNA | |
| SCHEMBL6540514 | 0.76 | UTS2R (0.51) | ALDH1A1KMT2AHTTS100A9LMNA | |
| SCHEMBL16235434 | 0.75 | S100A9 (0.68) | ALDH1A1KMT2AHTTS100A9LMNA | |
| SCHEMBL16235959 | 0.75 | S100A9 (0.69) | ALDH1A1KMT2AHTTS100A9LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004043463-A2 | SULFONAMIDES | SMITHKLINE BEECHAM CORPORATION (US) | 2004-05-27 | — | — | WO | disclosed |