Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 5/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | S100A9 | P06702 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.37 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8337846 | 0.81 | ALDH1A1 (0.53) | S100A9LMNAALDH1A1POLBMAPT | |
| SCHEMBL6674005 | 0.77 | UTS2R (0.58) | S100A9SCN9A | |
| SCHEMBL6674000 | 0.77 | UTS2R (0.58) | S100A9SCN9A | |
| SCHEMBL6674003 | 0.77 | S100A9 (0.37) | CCR2CYP3A4CYP2C9CYP2C19S100A9 | |
| SCHEMBL6818562 | 0.71 | UTS2R (0.58) | SCN9ASCN5A | |
| SCHEMBL8336957 | 0.71 | HSD17B2 (0.38) | S100A9LMNAALDH1A1POLBPGR | |
| SCHEMBL16235475 | 0.70 | S100A9 (0.45) | CCR2CYP3A4CYP2C9CYP2C19S100A9 | |
| SCHEMBL6825082 | 0.70 | SCN9A (0.35) | S100A9LMNAPOLBSCN9AMAPT | |
| SCHEMBL6676986 | 0.69 | S100A9 (0.36) | S100A9LMNAALDH1A1POLBSCN9A | |
| SCHEMBL6676981 | 0.69 | UTS2R (0.57) | S100A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004043463-A2 | SULFONAMIDES | SMITHKLINE BEECHAM CORPORATION (US) | 2004-05-27 | — | — | WO | disclosed |