Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SCN4A | P35499 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SCN1A | P35498 | 2/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3236165 | 0.79 | RAB9A (0.50) | KDM4EL3MBTL1GAAMAPTRAB9A | |
| SCHEMBL14985358 | 0.79 | KDM4E (0.49) | KDM4EL3MBTL1GAAMAPTRAB9A | |
| SCHEMBL27785923 | 0.77 | KDM4E (0.56) | KDM4EL3MBTL1GAAMAPTRAB9A | |
| SCHEMBL16572835 | 0.74 | KDM4E (0.45) | KDM4EL3MBTL1GAAMAPTRAB9A | |
| SCHEMBL13489644 | 0.74 | KDM4E (0.45) | KDM4EL3MBTL1GAAMAPTRAB9A | |
| SCHEMBL12129099 | 0.74 | KDM4E (0.62) | KDM4EL3MBTL1GAAMAPTRAB9A | |
| SCHEMBL8342697 | 0.73 | ALDH1A1 (0.48) | KDM4EL3MBTL1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL900180 | 0.72 | KDM4E (0.44) | KDM4EL3MBTL1GAAMAPTRAB9A | |
| SCHEMBL11233429 | 0.72 | RHEB (0.45) | KDM4EL3MBTL1GAAMAPTRAB9A | |
| SCHEMBL16957704 | 0.72 | KDM4E (0.44) | KDM4EL3MBTL1GAAMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004085408-A1 | 2, 3, 6-TRISUBSTITUTED-4-PYRIMIDONE DERIVATIVES | MITSUBISHI PHARMA CORPORATION (JP) | 2004-10-07 | — | — | WO | disclosed |