Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | SCN4A | P35499 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SCN1A | P35498 | 2/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9688509 | 0.85 | SCN4A (0.42) | L3MBTL1SCN9ASCN4ALMNASCN1A | |
| SCHEMBL16572835 | 0.82 | KDM4E (0.45) | KDM4EMAPTGAARAB9AL3MBTL1 | |
| SCHEMBL10359831 | 0.78 | KDM4E (0.42) | KDM4EMAPTGAARAB9AL3MBTL1 | |
| SCHEMBL900047 | 0.78 | ACHE (0.44) | L3MBTL1HTR1ASLC6A2SCN9ASCN4A | |
| SCHEMBL1918390 | 0.78 | HTR1A (0.41) | GAAHTR1ANPSR1SLC6A2SCN9A | |
| SCHEMBL24398990 | 0.77 | CYP1A2 (0.40) | HTR1ANPSR1SLC6A2LMNASLC6A4 | |
| SCHEMBL29402339 | 0.76 | TSHR (0.43) | HTR1ANPSR1SLC6A2SCN9ASLC6A4 | |
| SCHEMBL22366611 | 0.76 | TSHR (0.43) | HTR1ANPSR1SLC6A2SCN9ASLC6A4 | |
| SCHEMBL5733263 | 0.76 | ALDH1A1 (0.43) | GAAL3MBTL1HSP90AA1SCN9ASCN4A | |
| SCHEMBL900179 | 0.76 | ALDH1A1 (0.36) | MAPTHTR1ANPSR1SLC6A4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2621922-A1 | A PROCESS FOR THE SYNTHESIS OF THIO-TRIAZOLO-GROUP CONTAINING COMPOUNDS | BASF SE (DE) | 2013-08-07 | — | — | EP | disclosed |
| WO-2012041858-A1 | A PROCESS FOR THE SYNTHESIS OF THIO-TRIAZOLO-GROUP CONTAINING COMPOUNDS | BASF SE (DE) | 2012-04-05 | — | — | WO | disclosed |