Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100A9 | P06702 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 5/20 | 0.32 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6674003 | 0.92 | S100A9 (0.37) | S100A9MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL6679728 | 0.91 | S100A9 (0.37) | S100A9MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL6678341 | 0.90 | HPGD (0.41) | S100A9MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL6675715 | 0.88 | LMNA (0.39) | S100A9MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL6678442 | 0.87 | S100A9 (0.37) | S100A9MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL6822583 | 0.85 | PLA2G7 (0.38) | S100A9MEN1KMT2ALMNAPOLB | |
| SCHEMBL6672793 | 0.85 | ALDH1A1 (0.43) | S100A9MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL6825082 | 0.85 | SCN9A (0.35) | S100A9MEN1KMT2ALMNAPOLB | |
| SCHEMBL6824849 | 0.81 | LMNA (0.39) | S100A9MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL6825132 | 0.81 | FFAR4 (0.41) | S100A9MEN1KMT2AHPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004043463-A2 | SULFONAMIDES | SMITHKLINE BEECHAM CORPORATION (US) | 2004-05-27 | — | — | WO | claimed |
| WO-2004043463-A2 | SULFONAMIDES | SMITHKLINE BEECHAM CORPORATION (US) | 2004-05-27 | — | — | WO | disclosed |