SCHEMBL8338246

SCHEMBL8338246

CS(=O)(=O)c1ncc(C(=O)O)cc1C(F)(F)F

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ASPH Q12797 1/20 0.41
EGLN1 Q9GZT9 1/20 0.40
VNN1 O95497 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
ALKBH2 Q6NS38 1/20 0.36
ALKBH3 Q96Q83 1/20 0.36
FTO Q9C0B1 1/20 0.36
MALT1 Q9UDY8 1/20 0.36
PTGS1 P23219 1/20 0.36
PTGS2 P35354 1/20 0.36
SRD5A2 P31213 1/20 0.35
HCAR2 Q8TDS4 2/20 0.35
KDM4E B2RXH2 2/20 0.35
ALDH1A1 P00352 2/20 0.35
RORC P51449 1/20 0.35
GABRP O00591 1/20 0.35
GABRD O14764 1/20 0.35
GABRA1 P14867 1/20 0.35
GABRB1 P18505 1/20 0.35
GABRG2 P18507 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31030227 0.79 HCAR2 (0.42) ASPHEGLN1VNN1HCAR2KDM4E
SCHEMBL15074480 0.77 GLP1R (0.38) MALT1PTGS2NR1H2NR1H3GLP1R
SCHEMBL15052853 0.76 GLP1R (0.37) MALT1PTGS2NR1H2NR1H3GLP1R
SCHEMBL30254246 0.76 GLP1R (0.37) MALT1PTGS2NR1H2NR1H3GLP1R
SCHEMBL2705196 0.75 ASPH (0.46) ASPHVNN1L3MBTL1SRD5A2HCAR2
SCHEMBL3644389 0.73 ASPH (0.45) ASPHEGLN1VNN1L3MBTL1HCAR2
SCHEMBL15358062 0.73 MAP4K4 (0.47) ASPHVNN1L3MBTL1HCAR2KDM4E
SCHEMBL22530056 0.73 ASPH (0.45) ASPHEGLN1VNN1L3MBTL1HCAR2
SCHEMBL8342407 0.73 VNN1 (0.41) ASPHEGLN1VNN1L3MBTL1HCAR2
SCHEMBL2706774 0.73 L3MBTL1 (0.42) ASPHVNN1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4651907-A1 DRUG CONJUGATES AND METHODS OF PREPARING AND USING THE SAME Adcentrx Therapeutics Inc. (US) 2025-11-26 EP disclosed
WO-2024155761-A1 DRUG CONJUGATES AND METHODS OF PREPARING AND USING THE SAME ADCENTRX THERAPEUTICS INC. (US) 2024-07-25 WO disclosed
US-5968875-A FUNGICIDES FOR PLANTS DOW AGROSCIENCES LLC (US) 1999-10-19 US disclosed