Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 3/20 | 0.36 |
| ▸ | MMP13 | P45452 | 3/20 | 0.36 |
| ▸ | MMP1 | P03956 | 3/20 | 0.36 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | GPR88 | Q9GZN0 | 2/20 | 0.33 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8340431 | 0.94 | MMP9 (0.39) | TAS1R3TAS1R1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL8337089 | 0.93 | MMP9 (0.43) | TAS1R3TAS1R1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL8336514 | 0.93 | PKM (0.37) | CYP1A2CYP3A4CYP2C9PKMCYP2C19 | |
| SCHEMBL8336849 | 0.92 | MMP9 (0.44) | CYP1A2CYP3A4CYP2C9PKMCYP2C19 | |
| SCHEMBL8338207 | 0.90 | TDP1 (0.37) | TAS1R3TAS1R1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL8341137 | 0.86 | CYP1A2 (0.38) | CYP1A2CYP3A4CYP2C9PKMCYP2C19 | |
| SCHEMBL8339304 | 0.84 | MMP9 (0.42) | MMP9MMP13MMP1ADAM17CNR2 | |
| SCHEMBL8334100 | 0.84 | POLB (0.41) | TAS1R3TAS1R1MMP9MMP13MMP1 | |
| SCHEMBL8338140 | 0.84 | MMP9 (0.38) | TAS1R3TAS1R1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL8334670 | 0.83 | MMP9 (0.41) | CYP1A2CYP3A4CYP2C9PKMCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5977177-A | Substituted benzenesulfonylureas and-thioureas, processes for their preparation and use of pharmaceutical preparations based on these compounds, and medicaments containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-11-02 | — | — | US | disclosed |
| US-5880155-A | TREATMENT OF CARDIOVASCULAR DISORDERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-03-09 | — | — | US | disclosed |