Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.39 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | STS | P08842 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1564782 | 0.78 | KMT2A (0.68) | KMT2AALDH1A1CYP2A6SMN1; SMN2LMNA | |
| SCHEMBL784411 | 0.76 | ELANE (0.45) | KMT2AALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL11540230 | 0.72 | ALDH1A1 (0.44) | KMT2AALDH1A1CYP2A6SMN1; SMN2LMNA | |
| SCHEMBL2558556 | 0.71 | ADORA3 (0.56) | KMT2AALDH1A1CYP2A6SMN1; SMN2LMNA | |
| SCHEMBL10389057 | 0.70 | ALDH1A1 (0.50) | KMT2AALDH1A1CYP2A6SMN1; SMN2LMNA | |
| SCHEMBL814688 | 0.70 | PPARA (0.68) | ALDH1A1 | |
| SCHEMBL2559599 | 0.70 | KMT2A (0.45) | KMT2AALDH1A1CYP2A6SMN1; SMN2LMNA | |
| SCHEMBL14491042 | 0.70 | KMT2A (0.45) | KMT2AALDH1A1CYP2A6SMN1; SMN2LMNA | |
| SCHEMBL28665174 | 0.69 | ALDH1A1 (0.61) | KMT2AALDH1A1CYP2A6SMN1; SMN2LMNA | |
| SCHEMBL2559092 | 0.69 | PPARA (0.62) | KMT2AALDH1A1CYP2A6LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999007693-A1 | BENZOTHIOPHENES | ELI LILLY AND COMPANY (US) | 1999-02-18 | — | — | WO | disclosed |