Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 1/20 | 0.59 |
| ▸ | CTSK | P43235 | 1/20 | 0.59 |
| ▸ | KLK7 | P49862 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CASR | P41180 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | RORC | P51449 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31048635 | 0.91 | CTSK (0.66) | CTSSCTSKKLK7MAPTHDAC8 | |
| SCHEMBL8338149 | 0.91 | CTSK (0.66) | CTSSCTSKKLK7MAPTHDAC8 | |
| SCHEMBL27065693 | 0.89 | RORC (0.49) | CTSSCTSKMAPTALDH1A1KDM4E | |
| SCHEMBL8336332 | 0.89 | CTSS (0.60) | CTSSCTSKMAPTALDH1A1HTT | |
| SCHEMBL4597362 | 0.88 | CTSS (0.59) | CTSSCTSKKLK7HTTKMT2A | |
| SCHEMBL31560139 | 0.88 | CTSS (0.59) | CTSSCTSKMAPTALDH1A1KDM4E | |
| SCHEMBL8334410 | 0.88 | CTSS (0.59) | CTSSCTSKKLK7MAPTALDH1A1 | |
| SCHEMBL29866403 | 0.88 | CTSS (0.59) | CTSSCTSKMAPTALDH1A1KDM4E | |
| SCHEMBL8334434 | 0.88 | CTSS (0.59) | CTSSCTSKMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL8337402 | 0.88 | CTSS (0.59) | CTSSCTSKKLK7MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004022528-A2 | ARYLGLYCINE DERIVATIVES AND THEIR USE AS GLYCINE TRANSPORT INHIBITORS | NPS ALLELIX CORP. (CA) | 2004-03-18 | — | — | WO | disclosed |