Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPD1 | P10809 | 1/20 | 0.57 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.57 |
| ▸ | GSK3B | P49841 | 2/20 | 0.57 |
| ▸ | INSR | P06213 | 3/20 | 0.53 |
| ▸ | IGF1R | P08069 | 3/20 | 0.53 |
| ▸ | PIK3CG | P48736 | 7/20 | 0.52 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.50 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.50 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.50 |
| ▸ | GSK3A | P49840 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | NAT1 | P18440 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5164183 | 0.90 | GSK3B (0.67) | HSPD1HSPE1GSK3BINSRIGF1R | |
| SCHEMBL3895202 | 0.90 | GSK3B (0.67) | HSPD1HSPE1GSK3BINSRIGF1R | |
| SCHEMBL3895207 | 0.90 | GSK3B (0.67) | HSPD1HSPE1GSK3BINSRIGF1R | |
| SCHEMBL6388201 | 0.87 | HSPD1 (0.65) | HSPD1HSPE1GSK3BINSRIGF1R | |
| SCHEMBL6388205 | 0.87 | HSPD1 (0.65) | HSPD1HSPE1GSK3BINSRIGF1R | |
| SCHEMBL13855592 | 0.85 | HSPD1 (0.62) | HSPD1HSPE1GSK3BINSRIGF1R | |
| SCHEMBL3896735 | 0.84 | HSPD1 (0.61) | HSPD1HSPE1GSK3BINSRIGF1R | |
| SCHEMBL3896737 | 0.84 | HSPD1 (0.61) | HSPD1HSPE1GSK3BINSRIGF1R | |
| SCHEMBL3904211 | 0.79 | HSPD1 (0.72) | HSPD1HSPE1GSK3BINSRIGF1R | |
| SCHEMBL3904210 | 0.79 | HSPD1 (0.72) | HSPD1HSPE1GSK3BINSRIGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004043955-A1 | RHODANINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | RIGEL PHARMACEUTICALS, INC. (US) | 2004-05-27 | — | — | WO | disclosed |