Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPD1 | P10809 | 1/20 | 0.62 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.62 |
| ▸ | INSR | P06213 | 3/20 | 0.58 |
| ▸ | IGF1R | P08069 | 3/20 | 0.58 |
| ▸ | PIK3CG | P48736 | 5/20 | 0.57 |
| ▸ | GSK3B | P49841 | 2/20 | 0.55 |
| ▸ | GSK3A | P49840 | 1/20 | 0.55 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.55 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.55 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.50 |
| ▸ | NAT1 | P18440 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.49 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6388205 | 0.91 | HSPD1 (0.65) | HSPD1HSPE1INSRIGF1RPIK3CG | |
| SCHEMBL6388201 | 0.91 | HSPD1 (0.65) | HSPD1HSPE1INSRIGF1RPIK3CG | |
| SCHEMBL3896735 | 0.88 | HSPD1 (0.61) | HSPD1HSPE1INSRIGF1RPIK3CG | |
| SCHEMBL3896737 | 0.88 | HSPD1 (0.61) | HSPD1HSPE1INSRIGF1RPIK3CG | |
| SCHEMBL3895207 | 0.85 | GSK3B (0.67) | HSPD1HSPE1INSRIGF1RPIK3CG | |
| SCHEMBL5164183 | 0.85 | GSK3B (0.67) | HSPD1HSPE1INSRIGF1RPIK3CG | |
| SCHEMBL3895202 | 0.85 | GSK3B (0.67) | HSPD1HSPE1INSRIGF1RPIK3CG | |
| SCHEMBL8338948 | 0.85 | HSPD1 (0.57) | HSPD1HSPE1INSRIGF1RPIK3CG | |
| SCHEMBL3904211 | 0.83 | HSPD1 (0.72) | HSPD1HSPE1INSRIGF1RPIK3CG | |
| SCHEMBL3904210 | 0.83 | HSPD1 (0.72) | HSPD1HSPE1INSRIGF1RPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090137644-A1 | RHODANINE COMPOSITIONS FOR USE AS ANTIVIRAL AGENTS | RIGEL PHARMACEUTICALS, INC. (US) | 2009-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090137644-A1 | RHODANINE COMPOSITIONS FOR USE AS ANTIVIRAL AGENTS | RBX1, ITCH, UBQLN1 | HSPD1 2657/4885HSPE1 2257/4885INSR 4203/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.