Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 2/20 | 0.61 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.61 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.59 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.59 |
| ▸ | MAOA | P21397 | 1/20 | 0.59 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.59 |
| ▸ | HTR2C | P28335 | 1/20 | 0.59 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.59 |
| ▸ | HTR2B | P41595 | 1/20 | 0.59 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 5/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8342207 | 0.89 | TP53 (0.54) | SLC1A3SLC1A2SLC1A1MAOAROCK2 | |
| SCHEMBL8339578 | 0.86 | RAB9A (0.51) | SLC1A3SLC1A2SLC1A1CYP1A2ADRA2A | |
| SCHEMBL9447608 | 0.82 | NPC1 (0.65) | MAOAROCK2RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL20809837 | 0.81 | TP53 (0.56) | MAOAROCK2RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL11655760 | 0.81 | CYP1A2 (0.73) | SLC1A3SLC1A2SLC1A1CYP1A2ADRA2A | |
| SCHEMBL6191868 | 0.80 | NPC1 (0.57) | MAOAROCK2RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL6212186 | 0.79 | BAZ2B (0.57) | MAOAROCK2RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL3787405 | 0.78 | MGLL (0.58) | MAOAROCK2RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL19224991 | 0.77 | MEN1 (0.70) | MAOAROCK2RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL10305252 | 0.77 | ROCK2 (0.67) | MAOAROCK2RAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999003846-A1 | TRICYCLICALLY SUBSTITUTED OXAZOLIDINONES | BAYER AKTIENGESELLSCHAFT (DE) | 1999-01-28 | — | — | WO | disclosed |