Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.33 |
| ▸ | MAOA | P21397 | 3/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21698511 | 0.81 | MAOB (0.32) | MAOBMAOAOPRL1 | |
| SCHEMBL28662546 | 0.80 | CHRNB2 (0.33) | — | |
| SCHEMBL1783422 | 0.77 | — | — | |
| SCHEMBL1783456 | 0.77 | — | — | |
| SCHEMBL4045033 | 0.77 | ACHE (0.31) | — | |
| SCHEMBL6546814 | 0.73 | — | — | |
| SCHEMBL10811011 | 0.73 | MAOB (0.33) | MAOBMAOA | |
| SCHEMBL6548012 | 0.73 | — | — | |
| SCHEMBL6548053 | 0.70 | — | — | |
| SCHEMBL3976629 | 0.70 | CALM1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999009845-A1 | IMIDAZOQUINOXALINE PROTEIN TYROSINE KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-03-04 | — | — | WO | disclosed |