Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 3/20 | 0.48 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.44 |
| ▸ | CTRC | Q99895 | 1/20 | 0.44 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4423913 | 0.92 | TYR (0.48) | TYRTLR8CYP3A4MAPTMEN1 | |
| SCHEMBL1232399 | 0.89 | SKP2 (0.44) | TYRTLR8CTRCSKP2CYP3A4 | |
| SCHEMBL833911 | 0.88 | TYR (0.44) | TYRTLR8CTRCSKP2CYP3A4 | |
| SCHEMBL24677644 | 0.87 | TYR (0.40) | TYRTLR8CTRCSKP2CYP3A4 | |
| SCHEMBL27521449 | 0.87 | TYR (0.53) | TYRCYP3A4MAPTMEN1TP53 | |
| SCHEMBL3676124 | 0.85 | TLR8 (0.46) | TYRTLR8CYP3A4ALOX5LIPG | |
| SCHEMBL9027471 | 0.84 | TYR (0.43) | TYRTLR8SKP2CYP3A4MAPT | |
| SCHEMBL28193225 | 0.83 | TYR (0.44) | TYRTLR8SKP2CYP3A4MAPT | |
| SCHEMBL842068 | 0.83 | TYR (0.40) | TYRTLR8CTRCSKP2CYP3A4 | |
| SCHEMBL10342533 | 0.83 | SKP2 (0.47) | TYRTLR8CTRCSKP2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170260319-A1 | HYBRID NOVOLAC POLYUREA/POLYURETHANE | PPG INDUSTRIES OHIO, INC. | 2017-09-14 | — | — | US | disclosed |
| WO-2013009372-A1 | PHOSPHORUS-CONTAINING SECONDARY AMINE COMPOUNDS | HUNTSMAN PETROCHEMICAL LLC (US) | 2013-01-17 | — | — | WO | disclosed |
| CN-101516948-B | Diamine chain extender compositions | ALBEMARLE CORP | 2012-08-15 | — | — | CN | disclosed |
| CN-101568566-B | Formulations for reaction injection molding and for spray systems | ALBEMARLE CORP | 2012-07-11 | — | — | CN | disclosed |
| US-8212078-B2 | Making chain extenders with slower cure rates; reacting a ketone and/or aldehyde with a primary amine in the presence of an acidic ion exchange resin and hydrogenation agent; making diimine same way but excluding hydrogenation agent; e.g. N,N'-di-5-nonyl-isophoronediamine | ALBEMARLE CORPORATION (US) | 2012-07-03 | — | — | US | disclosed |
| US-8143365-B2 | Formulations for reaction injection molding and for spray systems | ALBEMARLE CORPORATION (US) | 2012-03-27 | — | — | US | disclosed |
| US-8080626-B2 | Chain extenders | ALBEMARLE CORPORATION (US) | 2011-12-20 | — | — | US | disclosed |
| US-7964695-B2 | Chain extenders | ALBEMARLE CORPORATION (US) | 2011-06-21 | — | — | US | disclosed |
| US-20110137005-A1 | Chain Extenders | ALBEMARLE CORPORATION (US) | 2011-06-09 | — | — | US | disclosed |
| CN-101891629-A | Diimine and secondary diamine | ALBEMARLE CORP | 2010-11-24 | — | — | CN | disclosed |
| CN-101160283-A | Diimines and secondary diamines | ALBEMARLE CORP (US) | 2008-04-09 | — | — | CN | disclosed |
| WO-2008039571-A1 | DIAMINE CHAIN EXTENDER COMPOSITIONS | ALBEMARLE CORPORATION (US) | 2008-04-03 | — | — | WO | disclosed |
| WO-2008039715-A1 | CHAIN EXTENDERS | ALBEMARLE CORPORATION (US) | 2008-04-03 | — | — | WO | disclosed |
| US-20080033210-A1 | DIIMINES AND SECONDARY DIAMINES | ALBEMARLE CORPORATION (US) | 2008-02-07 | — | — | US | disclosed |
| US-20080004406-A1 | DIIMINES AND SECONDARY DIAMINES | ALBEMARLE CORPORATION (US) | 2008-01-03 | — | — | US | disclosed |
| EP-1868987-A1 | DIIMINES AND SECONDARY DIAMINES | ALBEMARLE CORPORATION (US) | 2007-12-26 | — | — | EP | disclosed |
| US-20070270566-A1 | Chain Extenders | ALBEMARLE CORPORATION (US) | 2007-11-22 | — | — | US | disclosed |
| US-7288677-B2 | Diimines and secondary diamines | ALBEMARLE CORPORATION (US) | 2007-10-30 | — | — | US | disclosed |
| WO-2006104528-A1 | DIIMINES AND SECONDARY DIAMINES | ALBEMARLE CORPORATION (US) | 2006-10-05 | — | — | WO | disclosed |
| US-20060217567-A1 | Diimines and secondary diamines | ALBEMARLE CORPORATION | 2006-09-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080004406-A1 | DIIMINES AND SECONDARY DIAMINES | DDT, DDC, AOC1 | TYR 11/4885TLR8 437/4885CTRC 1493/4885 |
| US-20070270566-A1 | Chain Extenders | DDC, PARG, ODC1 | TYR 1763/4885TLR8 1170/4885CTRC 1045/4885 |
| US-20080033210-A1 | DIIMINES AND SECONDARY DIAMINES | DDT, DDC, AOC1 | TYR 11/4885TLR8 437/4885CTRC 1493/4885 |
| US-20060217567-A1 | Diimines and secondary diamines | DDT, DDC, AOC1 | TYR 11/4885TLR8 437/4885CTRC 1493/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.