Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.35 |
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | CASP1 | P29466 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8302824 | 0.79 | PDE4A (0.38) | MAPTKDM4ELMNAALDH1A1MEN1 | |
| SCHEMBL8293359 | 0.77 | ADORA2B (0.40) | KDM4ETDP1LMNAALDH1A1ALOX15 | |
| SCHEMBL7684767 | 0.72 | ALDH1A1 (0.40) | MAPTKDM4EATMTDP1LMNA | |
| SCHEMBL316396 | 0.72 | — | — | |
| SCHEMBL8340428 | 0.69 | GAA (0.41) | KDM4EATMALDH1A1ALOX15HTT | |
| SCHEMBL8676869 | 0.68 | NPSR1 (0.49) | MAPTKDM4ETDP1LMNAALDH1A1 | |
| SCHEMBL1423814 | 0.67 | ALDH1A1 (0.41) | LMNAALDH1A1NPSR1USP2MEN1 | |
| SCHEMBL196177 | 0.67 | ALDH1A1 (0.49) | ALDH1A1NPSR1USP2MEN1KMT2A | |
| SCHEMBL62015 | 0.65 | ALDH1A1 (0.40) | KDM4ELMNAALDH1A1ALOX15HSD17B10 | |
| SCHEMBL9269668 | 0.65 | ALDH1A1 (0.40) | KDM4ELMNAALDH1A1ALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5861420-A | ANGIOTENSIN II ANTAGONISTS | G. D. SEARLE & CO. (US) | 1999-01-19 | — | — | US | disclosed |