Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 5/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CALML3 | P27482 | 4/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.48 |
| ▸ | SDHA | P31040 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8342851 | 0.92 | CYP3A4 (0.47) | MAOACYP3A4CYP2D6CALML3MAOB | |
| SCHEMBL8339618 | 0.89 | CYP3A4 (0.45) | MAOACYP3A4CYP2D6CALML3MAOB | |
| SCHEMBL10423881 | 0.87 | ABCB11 (0.51) | MAOACYP3A4CYP2D6CALML3MAOB | |
| SCHEMBL21324902 | 0.87 | ABCB11 (0.51) | MAOACYP3A4CYP2D6CALML3MAOB | |
| SCHEMBL7938096 | 0.86 | MAOA (0.54) | MAOACYP3A4CYP2D6CALML3MAOB | |
| SCHEMBL8484607 | 0.86 | MAOA (0.66) | MAOACYP3A4CYP2D6CALML3MAOB | |
| SCHEMBL7949645 | 0.86 | MAOA (0.66) | MAOACYP3A4CYP2D6CALML3MAOB | |
| SCHEMBL7945883 | 0.85 | MAOA (0.54) | MAOACYP3A4CYP2D6CALML3MAOB | |
| SCHEMBL10435848 | 0.85 | MAOA (0.50) | MAOACYP3A4CYP2D6CALML3MAOB | |
| Hydrochloric Acid SCHEMBL8338829 | 0.84 | CYP3A4 (0.51) | MAOACYP3A4CYP2D6CALML3F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999003846-A1 | TRICYCLICALLY SUBSTITUTED OXAZOLIDINONES | BAYER AKTIENGESELLSCHAFT (DE) | 1999-01-28 | — | — | WO | disclosed |