Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.51 |
| ▸ | MAOA | P21397 | 5/20 | 0.51 |
| ▸ | MAOB | P27338 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | CALML3 | P27482 | 1/20 | 0.51 |
| ▸ | SDHA | P31040 | 1/20 | 0.51 |
| ▸ | F10 | P00742 | 5/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10423881 | 1.00 | ABCB11 (0.51) | ABCB11MAOAMAOBLMNAPTGS1 | |
| SCHEMBL10435848 | 0.93 | MAOA (0.50) | ABCB11MAOAMAOBLMNAPTGS1 | |
| SCHEMBL8489164 | 0.88 | MAOA (0.55) | ABCB11MAOAMAOBLMNAPTGS1 | |
| SCHEMBL8489161 | 0.88 | MAOA (0.55) | ABCB11MAOAMAOBLMNAPTGS1 | |
| SCHEMBL9550299 | 0.88 | MAOA (0.57) | ABCB11MAOAMAOBLMNAPTGS1 | |
| SCHEMBL9550276 | 0.88 | MAOA (0.57) | ABCB11MAOAMAOBLMNAPTGS1 | |
| SCHEMBL13298924 | 0.88 | MAOA (0.61) | ABCB11MAOAMAOBLMNAPTGS1 | |
| SCHEMBL8339574 | 0.87 | MAOA (0.51) | ABCB11MAOAMAOBLMNAPTGS1 | |
| SCHEMBL8311415 | 0.87 | MAOA (0.55) | ABCB11MAOAMAOBLMNAPTGS1 | |
| SCHEMBL8484607 | 0.86 | MAOA (0.66) | MAOAMAOBLMNAPTGS1CALML3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11807623-B2 | Nucleic acid-binding photoprobes and uses thereof | ARRAKIS THERAPEUTICS, INC. (US) | 2023-11-07 | — | — | US | disclosed |
| US-11807623-B2 | Nucleic acid-binding photoprobes and uses thereof | ARRAKIS THERAPEUTICS, INC. (US) | 2023-11-07 | — | — | US | disclosed |
| US-20230312520-A1 | NUCLEIC ACID-BINDING PHOTOPROBES AND USES THEREOF | ARRAKIS THERAPEUTICS, INC. | 2023-10-05 | — | — | US | disclosed |
| US-20230312520-A1 | NUCLEIC ACID-BINDING PHOTOPROBES AND USES THEREOF | ARRAKIS THERAPEUTICS, INC. | 2023-10-05 | — | — | US | disclosed |
| US-20190270723-A1 | NUCLEIC ACID-BINDING PHOTOPROBES AND USES THEREOF | ARRAKIS THERAPEUTICS, INC. | 2019-09-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190270723-A1 | NUCLEIC ACID-BINDING PHOTOPROBES AND USES THEREOF | NSUN3, NSUN2, TARBP1 | ABCB11 4278/4885MAOA 2886/4885MAOB 1343/4885 |
| US-20230312520-A1 | NUCLEIC ACID-BINDING PHOTOPROBES AND USES THEREOF | NSUN3, NSUN2, TARBP1 | ABCB11 4278/4885MAOA 2886/4885MAOB 1343/4885 |
| US-11807623-B2 | Nucleic acid-binding photoprobes and uses thereof | NSUN3, NSUN2, TARBP1 | ABCB11 4278/4885MAOA 2886/4885MAOB 1343/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.