Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.70 |
| ▸ | HPGD | P15428 | 4/20 | 0.70 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.70 |
| ▸ | MAPT | P10636 | 6/20 | 0.67 |
| ▸ | GAA | P10253 | 2/20 | 0.67 |
| ▸ | NPC1 | O15118 | 6/20 | 0.63 |
| ▸ | RAB9A | P51151 | 7/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12402761 | 0.88 | RAB9A (0.69) | TRPM8SMN1; SMN2ALDH1A1HPGDNPSR1 | |
| SCHEMBL28931086 | 0.86 | TRPM8 (0.58) | TRPM8SMN1; SMN2ALDH1A1HPGDNPSR1 | |
| SCHEMBL8345120 | 0.85 | MAPT (0.57) | TRPM8SMN1; SMN2ALDH1A1HPGDNPSR1 | |
| SCHEMBL8339292 | 0.85 | SMN1; SMN2 (0.72) | TRPM8SMN1; SMN2ALDH1A1HPGDMAPT | |
| SCHEMBL1316281 | 0.85 | CDC7 (0.77) | TRPM8SMN1; SMN2ALDH1A1HPGDNPSR1 | |
| SCHEMBL15048954 | 0.84 | TRPM8 (1.00) | TRPM8SMN1; SMN2ALDH1A1HPGDNPSR1 | |
| SCHEMBL974923 | 0.84 | TRPM8 (0.73) | TRPM8SMN1; SMN2ALDH1A1HPGDNPSR1 | |
| SCHEMBL16312760 | 0.84 | SMN1; SMN2 (0.66) | TRPM8SMN1; SMN2ALDH1A1HPGDNPSR1 | |
| SCHEMBL1327631 | 0.83 | SMN1; SMN2 (1.00) | SMN1; SMN2ALDH1A1HPGDNPSR1MAPT | |
| Methane SCHEMBL9629328 | 0.83 | TRPM8 (0.97) | TRPM8SMN1; SMN2ALDH1A1HPGDNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110184186-A1 | PROCESS FOR PREPARING LIGANDS OF PPARDELTA AND THE INTERMEDIATE COMPOUNDS FOR PREPARING THE SAME | SEOUL NATIONAL UNIVERSITY INDUSTRY FOUNDATION (KR) | 2011-07-28 | — | — | US | disclosed |
| US-7982050-B2 | Process for preparing ligands of PPARdelta and the intermediate compounds for preparing the same | SEOUL NATIONAL UNIVERSITY INDUSTRY FOUNDATION (KR) | 2011-07-19 | — | — | US | disclosed |
| US-20090118516-A1 | Process for preparing ligands of ppardelta and the intermediate compounds for preparing the same | Kang, Heon Joong (KR) | 2009-05-07 | — | — | US | disclosed |
| US-20070179300-A1 | Process for preparing thiazole derivative and the intermediate compounds for preparing the same | SEOUL NATIONAL UNIVERSITY INDUSTRY FOUNDATION (KR) | 2007-08-02 | — | — | US | disclosed |
| US-7241901-B2 | Process for preparing thiazole derivative and the intermediate compounds for preparing the same | SEOUL NATIONAL UNIVERSITY INDUSTRY FOUNDATION (KR) | 2007-07-10 | — | — | US | disclosed |
| US-5888941-A | Carbozamides with antifungal activity | J. URIACH & CIA. S.A. (ES) | 1999-03-30 | — | — | US | disclosed |
| EP-0783502-A1 | NEW CARBOXAMIDES WITH ANTIFUNGAL ACTIVITY | J. URIACH & CIA. S.A. (ES) | 1997-07-16 | — | — | EP | disclosed |
| WO-1997005131-A1 | NEW CARBOXAMIDES WITH ANTIFUNGAL ACTIVITY | J. URIACH & CIA. S.A. (ES) | 1997-02-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070179300-A1 | Process for preparing thiazole derivative and the intermediate compounds for preparing the same | PPARD, PPARG, PPARA | TRPM8 1841/4885SMN1; SMN2 4743/4885ALDH1A1 816/4885 |
| US-20110184186-A1 | PROCESS FOR PREPARING LIGANDS OF PPARDELTA AND THE INTERMEDIATE COMPOUNDS FOR PREPARING THE SAME | PPARG, PPARD, PPARA | TRPM8 2785/4885SMN1; SMN2 4828/4885ALDH1A1 1346/4885 |
| US-20090118516-A1 | Process for preparing ligands of ppardelta and the intermediate compounds for preparing the same | PPARG, PPARD, PPARA | TRPM8 2785/4885SMN1; SMN2 4828/4885ALDH1A1 1346/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.