Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | MMP9 | P14780 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | ACACB | O00763 | 1/20 | 0.51 |
| ▸ | ACACA | Q13085 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | F7 | P08709 | 2/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.50 |
| ▸ | F10 | P00742 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | PDE2A | O00408 | 1/20 | 0.48 |
| ▸ | METAP2 | P50579 | 1/20 | 0.46 |
| ▸ | METAP1 | P53582 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8339684 | 1.00 | HCRTR1 (0.62) | HCRTR1TDP1MMP9TSHRRECQL | |
| SCHEMBL1143366 | 0.84 | MMP9 (0.64) | HCRTR1TDP1MMP9TSHRMEN1 | |
| SCHEMBL3523094 | 0.84 | MMP9 (0.64) | HCRTR1TDP1MMP9TSHRMEN1 | |
| SCHEMBL18068729 | 0.84 | MMP9 (0.64) | HCRTR1TDP1MMP9TSHRACACB | |
| SCHEMBL7931673 | 0.84 | MMP9 (0.64) | HCRTR1TDP1MMP9TSHRMEN1 | |
| SCHEMBL4037714 | 0.82 | ALDH1A1 (0.64) | HCRTR1TDP1MMP9MEN1KMT2A | |
| SCHEMBL4857933 | 0.82 | ALDH1A1 (0.64) | HCRTR1TDP1MMP9MEN1KMT2A | |
| SCHEMBL1321496 | 0.82 | MMP9 (0.66) | HCRTR1TDP1MMP9TSHRACACB | |
| SCHEMBL5016632 | 0.82 | TSHR (0.73) | TSHRMEN1KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL16714724 | 0.82 | TSHR (0.73) | TSHRMEN1KMT2AHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5922899-A | Carbamoyl carboxylic acid amides | BASF AKTIENGESELLSCHAFT (DE) | 1999-07-13 | — | — | US | disclosed |